News & Publications

March 9, 2016

Toxicity testing of combustion aerosols at the air-liquid interface with a self-contained and easy-to-use exposure system

doi:10.1016/j.jaerosci.2016.02.005 Sonja Mülhopt a, i, Marco Dilger a, b, i, Silvia Diabaté b, i, Christoph Schlager a, i, Tobias Krebs […]

January 8, 2016

Carbonbeton – eine neue Art des Bauens

VITROCELL® Systems GmbH ist Teil dieses größten Bauforschungsprojektes Deutschlands, dem Projekt C³-Carbon Concrete Composite. Zusammen mit mehr als 130 Partnern […]

October 31, 2015

Roflumilast partially reverses smoke-induced mucociliary dysfunction

DOI 10.1186/s12931-015-0294-3 Andreas Schmid, Nathalie Baumlin, Pedro Ivonnet, John S. Dennis, Michael Campos, Stefanie Krick and Matthias Salathe* * Correspondence: […]

September 29, 2015

Assessment of a panel of interleukin-8 reporter lung epithelial cell lines to monitor the pro-inflammatory response following zinc oxide nanoparticle exposure

DOI 10.1186/s12989-015-0104-6 Linda C. Stoehr1,2†, Carola Endes3†, Isabella Radauer-Preiml1, Matthew S. P. Boyles1, Eudald Casals4, Sandor Balog5, Markus Pesch2, Alke […]

September 23, 2015

Toxicological validation during the development of new catalytic systems using air / liquid interface cell exposure system

Authors Y. Landkocz1, M. Al Zallouha1, J. Brunet2, R. Cousin2, J.M. Halket3, E. Genty2, D. Courcot1, S. Siffert2, P. Shirali1, […]

September 23, 2015

Airway epithelium co-cultured with immune cells for a better assessment of the low dose effects of environmental pollutants

Authors Emilie RICQUEBOURG, Gabrielle VERNOUILLET, Isabelle MOMAS, Nathalie SETA, Sophie ACHARD Public Health and Environment Laboratory, EA4064 – Paris Descartes […]

September 23, 2015

A comparative assessment of cigarette smoke aerosols using an in vitro air-liquid interface cytotoxicity test.

DOI:10.3109/08958378.2015.1080773 Authors Thorne D, Dalrymple A, Dillon D, Duke M, Meredith C British American Tobacco, Group R&D, Southampton, Hampshire, UK. […]

July 12, 2015

Development of an in vitro cytotoxicity model for aerosol exposure using 3D reconstructed human airway tissue; application for assessment of e-cigarette aerosol

DOI:10.1016/j.tiv.2015.05.018 Authors Louise Neilsona, Courtney Mankusb, David Thornea, George Jacksonb, Jason DeBayb, Clive Mereditha a British American Tobacco, Group Research […]

June 27, 2015

Translocation of gold nanoparticles across the lung epithelial tissue barrier: Combining in vitro and in silico methods to substitute in vivo experiments

DOI 10.1186/s12989-015-0090-8 Gerald Bachler1,2, Sabrina Losert1,3, Yuki Umehara2, Natalie von Goetz1*, Laura Rodriguez-Lorenzo2, Alke Petri-Fink2, Barbara Rothen-Rutishauser2 and Konrad Hungerbuehler1 […]

June 3, 2015

Particulate Matter from Both Heavy Fuel Oil and Diesel Fuel Shipping Emissions Show Strong Biological Effects on Human Lung Cells at Realistic and Comparable In Vitro Exposure Conditions

DOI: 10.1371/journal.pone.0126536 Authors Sebastian Oeder , Tamara Kanashova , Olli Sippula , Sean C. Sapcariu , Thorsten Streibel , Jose […]

March 21, 2015

Automatisiertes Expositionssystem für Zellkulturen an der Gas-Flüssigkeits-Grenzschicht

(Automated exposure system for cell cultures at the air/liquid interface / article in German) Authors Sonja Mülhopt, Tobias Krebs, Dr. […]

March 5, 2015

The mutagenic assessment of mainstream cigarette smoke using the Ames assay: A multi-strain approach

doi:10.1016/j.mrgentox.2015.03.006 Authors David Thornea, Joanne Kilfordb, Michael Hollingsb, Annette Dalrymplea, Mark Ballantyneb, Clive Mereditha, Deborah Dillona a British American Tobacco, […]

February 20, 2015

Repeated exposure to carbon nanotube-based aerosols does not affect the functional properties of a 3D human epithelial airway model

Nanotoxicology, Early Online: 1–11 (doi: 10.3109/17435390.2014.993344) Authors Savvina Chortarea1, Martin J. D. Clift1, Dimitri Vanhecke1, Carola Endes1, Peter Wick2, Alke […]

February 12, 2015

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke

jove, 12 Februray 2015, Issue 96 (doi: 10.3791/52325) Authors Diana Kuehn1, Shoaib Majeed1, Emmanuel Guedj1, Remi Dulize1, Karine Baumer1, Anita […]

November 12, 2014

Characterization of the Vitrocell® 24/48 in vitro aerosol exposure system using mainstream cigarette smoke

doi:10.1186/s13065-014-0062-3 Authors Shoaib Majeed1, Stefan Frentzel1, Sandra Wagner2, Diana Kuehn1, Patrice Leroy1, Philippe A. Guy1, Arno Knorr1, Julia Hoeng1 and […]

October 30, 2014

Comparative In Vitro Toxicity Profile of Electronic and Tobacco Cigarettes, Smokeless Tobacco and Nicotine Replacement Therapy Products: E-Liquids, Extracts and Collected Aerosols

11325-11347; doi:10.3390/ijerph111111325 Authors Manoj Misra, Robert D. Leverette, Bethany T. Cooper, Melanee B. Bennett and Steven E. Brown Lorillard Tobacco […]

October 30, 2014

An inter-machine comparison of tobacco smoke particle deposition in vitro from six independent smoke exposure systems

Volume 28, Issue 7, October 2014, Pages 1320-1328 (doi: 10.1016/j.tiv.2014.06.012) Authors J. Adamsona, D. Thornea, G. Erringtona, W. Fieldsb, X. […]

October 8, 2014

The Response of Human Nasal and Bronchial Organotypic Tissue Cultures to Repeated Whole Cigarette Smoke Exposure

Authors Marja Talikka1, Radina Kostadinova1, Yang Xiang1, Carole Mathis1, Alain Sewer1, Shoaib Majeed1, Diana Kuehn1, Stefan Frentzel1, Celine Merg1, Marcel […]

September 23, 2014

An in vitro testing strategy towards mimicking the inhalation of high aspect ratio nanoparticles

Particle and Fibre Toxicology 2014, 11:40 (doi:10.1186/s12989-014-0040-x) Authors Carola Endes1, Otmar Schmid2, Calum Kinnear1, Silvana Mueller3, Sandra Camarero-Espinosa3, Dimitri Vanhecke1, […]

September 19, 2014

Silica nanoparticles are less toxic to human lung cells when deposited at the air-liquid interface compared to conventional submerged exposure

2014, 5, 1590–1602 (doi:10.3762/bjnano.5.171) Authors Alicja Panas1, Andreas Comouth2, Harald Saathoff2, Thomas Leisner2, Marco Al-Rawi1, Michael Simon3, Gunnar Seemann3, Olaf […]

July 21, 2014

In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures

informa healthcare, posted online on July 21, 2014. (doi:10.3109/15376516.2014.943441) Authors Walter K. Schlage*, Anita R. Iskandar*, Radina Kostadinova*, Yang Xiang*, […]

July 15, 2014

A method for assessment of the genotoxicity of mainstream cigarette-smoke by use of the bacterial reverse-mutation assay and an aerosol-based exposure system

Volume 769, 15 July 2014, Pages 20–28, [epub ahead of print] Authors Joanne Kilforda, David Thorneb, Rebecca Paynea, Annette Dalrympleb, […]

June 30, 2014

Transforming Growth Factor β1 and Cigarette Smoke Inhibit the Ability of β2-Agonists to Enhance Epithelial Permeability

www.atsjournals.org published on June 30, 2014 (doi: 10.1165/rcmb.2013-0538OC) Authors Hoshang J. Unwalla1, Pedro Ivonnet1, John S. Dennis, Gregory E. Conner1,2, […]

June 21, 2014

A model of human nasal epithelial cells adapted for direct and repeated exposure to airborne pollutants

2014 Jun 21;229(1):144-149. doi: 10.1016/j.toxlet.2014.05.023. Epub ahead of print. Authors Bardet G.1, Achard S.2, Loret T.3, Desauziers V.4, Momas I.5, […]

June 17, 2014

Development of a BALB/c 3T3 neutral red uptake cytotoxicity test using a mainstream cigarette smoke exposure system

BMC Research Notes 2014, 7:367 (doi:10.1186/1756-0500-7-367) Authors David Thorne1, Joanne Kilford2, Rebecca Payne2, Linsey Haswell1, Annette Dalrymple1, Clive Meredith1 and […]

June 2, 2014

Application of a modified gaseous exposure system to the in vitro toxicological assessment of tobacco smoke toxicants

Volume 55, Issue 8, Article first published online: 2 JUN 2014 (doi: 10.1002/em.21876) Authors Damien Breheny1, Fiona Cunningham1, Joanne Kilford2, […]

April 28, 2014

Efficient bioactive delivery of aerosolized drugs to human pulmonary epithelial cells cultured at air-liquid interface conditions

First published online 28 Apr 2014 (doi: 10.1165/rcmb.2013-0479OC) Authors Anke-Gabriele Lenz1, Tobias Stoeger1, Daniele Cei2, Martina Schmidmeir1, Nora Pfister1, Gerald […]

March 27, 2014

Potential toxicity of electronic cigarette liquids and aerosols as measured by four in vitro assays

24-27 March, 2014 Authors Leverette, R.D., Misra, M., Cooper, B.T. and Bennett, M.B. Lorillard Tobacco Company, A.W. Spears Research Center, […]

March 27, 2014

Cerium oxide nanoparticles air exposure: a comparison study using a human 3D airway model and A549 and Beas-2B cell lines

24-27 March, 2014 Authors Ingeborg M. Kooter1, Mariska Grollers-Mulderij1, Maaike Steenhof1, Evert Duistermaat2, Frederique van Acker2, Yvonne Staal2, Eric Schoen1, […]

November 1, 2013

A review of in vitro cigarette smoke exposure systems

Volume 65, Issues 7-8, November 2013, Pages 1183-1193. pii: S0940-2993(13)00081-X. doi: 10.1016/j.etp.2013.06.001. [Epub ahead of print] Authors Thorne D, Adamson […]

October 3, 2013

A modified Ames methodology for the assessment of mainstream cigarette smoke genotoxicity using an aerosol-based exposure system

29 September – 3 October 2013 Authors David Thorne1, Joanne Kilford2, Rebecca Payne2, Annette Dalrymple1, Julie Clements2, Clive Meredith1, Debbie […]

September 30, 2013

Modelling and measurement of particle deposition for cell exposure at the air-liquid interface

Volume 63, September 2013, Pages 103-114 Authors Andreas Comoutha, Harald Saathoffa, Karl-Heinz Naumanna, Sonja Muelhoptb, Hanns-Rudolf Paurb, Thomas Leisnera a […]

September 30, 2013

In vitro reconstituted human airway epithelium model to assess the impact of indoor air pollutants on the inflammatory response

September 2013 Authors Sophie Achard, Gaëlle Bardet, Sophie Grellet, Isabelle Momas, Nathalie Seta Université Paris Descartes, PRES Cité Sorbonne, Faculté […]

September 30, 2013

Comparison of epithelial cells inflammatory response from the human respiratory tract after formaldehyde exposure

September 2013 Authors Gaëlle Bardet1,2, Charles Persoz1, Thomas Loret1, Isabelle Momas1, Sophie Achard1, Nathalie Seta1 1 Université Paris Descartes, Faculté […]

September 30, 2013

A 4D lung multi-culture system mimicking alveolar cellular organization to study the toxic potential of airborne particles

September 2013 Authors T. Serchi1,∗,S.G. Klein1,2, A. Jehanno1, S. Legay1, S. Contal1, J. Hennen2, A.C. Gutleb1, L. Hoffmann1 and B. […]

September 30, 2013

Evaluation of a human in vitro 3D respiratory epithelium model in bioavailability and safety assessment of pharmaceutical and chemical compounds

September 2013 Authors Joost Vos1, Yvonne Staal1, Jos van Triel1, Frédérique van Acker1, Astrid Reus1, Evert Duistermaat1, Wilfred Maas1, Mariska […]

September 6, 2013

Comet assay and air-liquid interface exposure system: A new combination to evaluate genotoxic effects of cigarette whole smoke in human lung cell lines

Volume 27, Issue 6, September 2013, Pages 1987-1991. pii: S0887-2333(13)00168-9. doi: 10.1016/j.tiv.2013.06.016. [Epub ahead of print] Authors Weber S.1, Hebestreit […]

September 3, 2013

Characterisation of a Vitrocell® VC 10 in vitro smoke exposure system using dose tools and biological analysis

doi:10.1186/1752-153X-7-146 Authors David Thorne1, Joanne Kilford2, Rebecca Payne2, Jason Adamson1, Ken Scott1, Annette Dalrymple1, Clive Meredith1 and Deborah Dillon1 1 […]

July 29, 2013

Evaluation method for the cytotoxicity of cigarette smoke byin vitro whole smoke exposure

https://doi.org/10.1016/j.etp.2013.07.004 Xiang Li, Cong Nie, Pingping Shang, Fuwei Xie, Huimin Liu, Jianping Xie Key Laboratory of Tobacco Chemistry, Zhengzhou Tobacco […]

July 26, 2013

An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

doi:10.1186/1743-8977-10-31 Authors Sebastian G Klein12, Tommaso Serchi1, Lucien Hoffmann1, Brunhilde Blömeke2 and Arno C Gutleb1* 1 Department Environment and Agro-biotechnologies […]

March 14, 2013

THP-1 and HMC-1 cell interaction with epithelial cells in a 3D tetraculture system of the alveolar barrier modulates the response to oxidative stress

March 10-14, 2013 Authors Sebastian G. Klein1,2, Tommaso Serchi1, Lucien Hoffmann1, Brunhilde Blömeke2 and Arno C. Gutleb1 1 Dept. of […]

March 14, 2013

Assessment of dosimetry and biological responses in vitro using a Vitrocell® smoke exposure system

March 10-14, 2013 Authors David Thorne1, Joanne Kilford2, Rebecca Payne2, Jason Adamson1, Ken Scott1, Annette Dalrymple1, Clive Meredith1, Debbie Dillon1 […]

March 14, 2013

Comparison of a new skin penetration system containing a toxicokinetic module with Franz diffusion cells

March 10-14, 2013 Authors D. Gerstel, I. Herberz, M. Akhiani, S. Mueller , H. Wenck, A. Schepky Beiersdorf AG, Toxicology, […]

March 12, 2013

Assessment of cigarette smoke particle deposition within the Vitrocell® exposure module using quartz crystal microbalances

doi:10.1186/1752-153X-7-50 Authors Jason Adamson, David Thorne, Annette Dalrymple, Debbie Dillon, Clive Meredith British American Tobacco, Group R&D, Southampton SO15 8TL, […]

February 6, 2013

Optimization of the VITROCELL® Exposure System for in vitro toxicity testing of diesel emissions at the air-liquid interface

February 5-6, 2013 Authors Rebecca Greenan1, Tak Chan2, Mathias Könczöl3, Julie Bourdon1, Debbie Rosenblatt2, Marie-Josée Poitras2and Paul A. White1 1 […]

January 25, 2013

Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers

2013 Apr 1;304(7):L489-503. doi: 10.1152/ajplung.00181.2012. [Epub ahead of print] Authors Mathis C, Poussin C, Weisensee D, Gebel S, Hengstermann A, […]

December 7, 2012

Toxicological analysis of limonene reaction products using an in vitro exposure system

2013 Mar;27(2):721-30. doi: 10.1016/j.tiv.2012.11.017. [Epub ahead of print] Authors Anderson SE, Khurshid SS, Meade BJ, Lukomska E, Wells JR. Health […]

December 3, 2012

An Improved 3D Tetraculture System Mimicking the Cellular Organization at the Alveolar Barrier to Study the potential toxic Effects of Particles on the Lung

December 3, 2012. Best poster of a young scientist. Authors Sebastian G. Klein*1,2, Tommaso Serchi1, Lucien Hoffmann1, Brunhilde Blömeke2 and […]

October 31, 2012

Application of organotypic in vitro human cell culture models for research and development of inhalation pharmaceutical formulations targeting the proximal airways

Issue October 2012 Authors Patrick Hayden MatTek Corporation, Ashland, MA, US This article briefly reviews the application of organotypic […]

September 5, 2012

Validation of an in vitro exposure system for toxicity assessment of air-delivered nanomaterials

Sep 5, 2012. pii: S0887-2333(12)00252-4. [Epub ahead of print] Authors Kim JS, Peters TM, O'Shaughnessy PT, Adamcakova-Dodd A, Thorne PS. […]

June 20, 2012

Comparison of a new skin penetration system containing a toxicokinetic modul with Franz diffusion cells

June 17-20, 2012. Stockholm, Sweden. Authors D. Gerstel1, N. Metke2, S. Mueller1, I. Herberz1, M. Akhiani1, CD Wacker2, H. Wenck1, […]

April 19, 2012

Dose Determination of Airborne Particles for In Vitro Exposure at the Air / Liquid Interface

IVTIP Spring Meeting 2012. April 19, 2012, Bilbao, Spain. Authors Marco Hebestreit and Tobias Krebs Vitrocell Systems GmbH, Waldkirch, Germany […]

March 31, 2012

Inflammatory response modulation of airway epithelial cells exposed to formaldehyde

2012, 211(2):159-163. doi:10.1016/j.toxlet.2012.03.799 [Epub ahead of print] Authors Persoz C, Achard S, Momas I, Seta N. PRES Sorbonne Paris Cité, […]

March 15, 2012

Dosimetry Methods for Tobacco Smoke Aersosol In Vitro Exposures

March 11-15, 2012. Poster #1841 Authors Rainy Marsh1, Jessica Perkins2, Ken Scott2, Debbie Dillon2 and Clive Meredith2 1 British American […]

March 15, 2012

Impact of test conditions on in vitro cytotoxicity measurements of mainstream cigarette smoke using a whole smoke exposure system

March 11-15, 2012; Poster #1843 Authors Xiang Li, Pingping Shang, Cong Nie, Fuwei Xie, Huimin Liu, Jianping Xie Key Laboratory […]

March 15, 2012

Utilization of a whole smoke exposure system for the comparison of mainstream cigarette smoke, gas vapor phase and tar mutagenicity

March 11-15, 2012; Poster #1843 Authors Robert D. Leverette Life Sciences, A.W. Spears Research Center, Lorillard Tobacco Company, Greensboro, NC […]

December 16, 2011

Effects of smoking regimens and test material format on the cytotoxicity of mainstream cigarette smoke

2011 Dec 16; 50(3-4):545-551. [Epub ahead of print] Authors Li X, Shang P, Peng B, Nie C, Zhao L, Liu […]

December 1, 2011

Evaluating pulmonary toxicity of engineered metal-based nanoparticles using in vivo and in vitro models

November 8, 2011

Investigations on cytotoxic and genotoxic effects of laser printer emissions in human epithelial A549 lung cells using an air/liquid exposure system

November 8, 2011 (doi: 10.1002/em.20695) Authors Tang, T., Gminski, R., Könczöl, M., Modest, C., Armbruster, B. and Mersch-Sundermann, V. (2011) […]

September 28, 2011

Aerosolized ZnO nanoparticles induce toxicity in alveolar type II epithelial cells at the air-liquid interface

2012 Feb;125(2):450-61 (doi:10.1093/toxsci/kfr251) [Epub ahead of print] Authors Xie Y, Williams NG, Tolic A, Chrisler WB, Teeguarden JG, Maddux BL, […]

August 31, 2011

Effect of Formaldehyde On Corneal Epithelial Cells In An Air-Liquid Culture Model

August 28-31, 2011; Poster #P1198 Authors Françoise Brignole-Baudouin1,2,4, Sophie Achard3, Charles Persoz3, Alice Emptoz1,2, Nathalie Seta3, Christophe Baudouin1,2,4 1 UMR_S968 INSERM […]

August 31, 2011

In vitro model of repeated exposure to different contaminants of human respiratory cells

August 28-31, 2011; Poster #P1361 Authors Charles PERSOZ 1, Christopher LELEU 2, Sophie ACHARD 1, Magali FASSEU 3, Jean MENOTTI […]

August 31, 2011

Comparison of two in vitro models to assess the impact of environmentail pollutant exposures on respiratory cells

August 28-31, 2011; Poster #P1362 Authors Charles Persoz 1, Christopher Leleu 2, Sophie Achard 1, Isabelle Momas 1, Nathalie Seta […]

August 31, 2011

A novel dynamic gas mixing system to assess the human lung cells response to BTXE exposure at low levels

August 28-31, 2011; Poster #P2056 Authors Sophie ACHARD 1, Mathilde DELAVAL 1, Tobias KREBS 2, Isabelle MOMAS 1, Nathalie SETA […]

August 25, 2011

A novel approach to assess irritant or respiratory allergenic potential of chemicals in vitro

August 21-25, 2011 Authors Singal M.1, Vitale D.1, Smith L.1, Czollner K.2, Farmer L.2, Höpfner C.2, Satzer H-P.2, Schoeffmann S.2, […]

August 22, 2011

Prävalidierungsstudie zur Prüfung der toxischen Wirkung von inhalativ wirksamen Stoffen (Gase)

1. Auflage. Dortmund: Bundesanstalt für Arbeitsschutz und Arbeitsmedizin 2011 Authors G. Linsel, M. Bauer, E. Berger-Preiß, C. Gräbsch, H. Kock, […]

August 12, 2011

Ex vivo toxicity of nitrogen dioxide in human nasal epithelium at the WHO defined 1-h limit value

2011 Nov 10;207(1):89-95. doi: 10.1016/j.toxlet.2011.08.004. [Epub ahead of print] Authors C. Koehler, C. Ginzkey, G. Friehs, S. Hackenberg, K. Froelich, […]

August 5, 2011

Sequential air-liquid exposure of human respiratory cells to chemical and biological pollutants

2011 Nov 10;207(1):53-9. doi: 10.1016/j.toxlet.2011.07.028 [Epub ahead of print] Authors Persoz C, Leleu C., Achard S., Fasseu M., Menotti J., […]

March 10, 2011

Comparison of the bacterial mutagenicity of mainstream whole smoke from cigarettes with different levels of menthol

March 06-10, 2011 Authors Robert D. Leverette Life Sciences, A. W. Spears Research Center, Lorillard Tobacco Company, Greensboro, NC 27405, […]

March 10, 2011

In vitro exposure of organotypical 3D epithelial tissues to cigarette smoke as a potential alternative to rodent inhalation studies

March 06-10, 2011 Authors Weisensee, D., Kurkowsky, B., Hebestreit, M., Wagner, S. and Schueller J. Philip Morris Research Laboratories GmbH, Cologne, […]

July 23, 2010

Toxicological investigation of laser printer emissions – Effects on human cells

July 16-23, 2010 Authors Tao Tang, Richard Gminski, Rebecca Kuhn, Mathias Könczöl, Carsten Gründemann, Benedikt Armbruster, Volker Mersch-Sundermann Institute of […]

July 20, 2010

Untersuchungen zur genetischen Toxizität von Emissionen aus Laserdruckern in A549-Zellen im Vitrocell®-Transwell-Expositionssystem

Authors Tao Tang, Richard Gminski und Volker Mersch-Sundermann Department of Environmental Health Sciences, Institute of Environmental Medicine and Hospital Hygiene […]

June 30, 2010

Effects of acute in vitro exposure of murine precision-cut lung slices to gaseous nitrogen dioxide and ozone in an air-liquid interface (ALI) culture

2010 Jul 1;196(2):117-24. doi: 10.1016/j.toxlet.2010.04.004. [epub ahead of print] Authors S. Switalla, J. Knebel, D. Ritter, N. Krug, A. Braun, […]

March 31, 2010

Cytotoxicity and genotoxicity in human lung epithelial A549 cells caused by airborne volatile organic compounds emitted from pine wood and oriented strand boards

2010 Jun 16;196(1):33-41. doi: 10.1016/j.toxlet.2010.03.015. [epub ahead of print] Authors Gminski R, Tang T, Mersch-Sundermann V. Institute of Environmental Medicine […]

March 25, 2010

A novel in vitro micronucleus (MN) test procedure after exposure of human derived lung cells to volatile chemicals at the air/liquid interface in vitro

March 23-25, 2010 Authors Richard Gminski, Christoph Modest, Benedikt Armbruster, Tao Tang, Mathias Könczöl, Volker Mersch-Sundermann Department of Environmental Health […]

March 10, 2010

An in vitro model to evaluate the inflammatory response after gaseous formaldehyde exposure of lung epithelial cells

2010 Jun 2;195(2-3):99-105. doi: 10.1016/j.toxlet.2010.03.003. [epub ahead of print] Authors Persoz C., Achard S., Leleu C., Momas I., Seta N. […]

March 7, 2010

Aspects of nitrogen dioxide toxicity in environmental urban concentrations in human nasal epithelium.

2010 Jun 1;245(2):219-25. doi: 10.1016/j.taap.2010.03.003. [Epub ahead of print] Authors Koehler C., Ginzkey C., Friehs G., Hackenberg S., Froelich K., […]

March 3, 2010

Evaluation of Dicarbonyls Generated in a Simulated Indoor Air Environment Using an in Vitro Exposure System

2010 Jun;115(2):453-61. doi: 10.1093/toxsci/kfq067. [Epub ahead of print] Authors Anderson SE, Jackson LG, Franko J., Wells JR. National Institute for […]

January 14, 2010

A biological test for environmental toxins

Highlights from Baden-Württemberg, January 14, 2010 Authors Dr. rer. nat. Richard Gminski Institute of Environmental Medicine and Hospital Hygiene (IUK), […]

September 16, 2009

Cytokine Production after Acute Exposure of Precision Cut Lung Slices to NO2 and O3

September 13-16, 2009 Authors K. Sewald, S. Switalla, D. Ritter, N. Krug, J. Knebel, A. Braun Fraunhofer Institute for Toxicology […]

September 16, 2009

An in vitro model to assess the impact on respiratory cells (A549) of air pollution

September 13-16, 2009. Bo Holmstedt Authors Charles Persoz, Sophie Achard, Christopher Leleu, Isabelle Momas, Nathalie Seta Laboratoire Sante Publique et […]

September 11, 2009

Biological effects in human lung cells exposed to platinum nanoparticle aerosol

September 06-11, 2009 Authors S. Diabaté, C. Weiss, S. Mülhopt, H.-R. Paur, V. Niedetzky, M. Seipenbusch Institute for Toxicology and […]

September 11, 2009

Toxic effects of nanoparticles from biomass combustion

September 06-11, 2009 Authors Werner Fr. Dreher, Frank Weise, Karen Böhme, Steffen Lutz, Michael Struschka, Johannes Brodbeck, Sonja Mülhopt, Hanns-Rudolf […]

September 11, 2009

The QCM – Online Dose Measurement with high relative Humidity

September 06-11, 2009 Authors S. Mülhopt, A. Comouth, A. Grotz, T. Krebs, H.-R. Paur Institute for Technical Chemistry, Thermal Waste […]

September 3, 2009

Air/Liquid Culture and Exposure Technique: Preliminary Results of a Prevalidation Study

August 30 – September 3, 2009 Authors Smirnova, L.1, Liebsch, M.1, Tharmann, J.1, Pirow, R.1, Luch, A.1, Bauer, M.2, Graebsch, […]

March 23, 2009

Lung toxicity determination by in vitro exposure at the air-liquid interface with an integrated online dose measurement

Journal of Physics: Conference Series 170 (2009) 012008 (doi:10.1088/1742-6596/170/1/012008) Authors Sonja Mülhopt, S. Diabaté, T. Krebs, C. Weiss and H.-R. […]

March 19, 2009

Identification of Indoor Air Contaminants Using an in Vitro Exposure System

March 15-19, 2009 Authors Laurel G. Jackson, J. R. Wells, Jason Ham, Albert Munson, and Stacey E. Anderson National Institute […]

October 8, 2008

Online dose determination for in vitro experiments with nano particles in the Karlsruhe Exposure System

October 5-8, 2008 Authors S. Mülhopt, H.-R. Paur, T. Krebs Forschungszentrum Karlsruhe, Eggenstein – Leopoldshafen, Germany VITROCELL Systems GmbH, Waldkirch, […]

March 10, 2008

The Response of a Co-culture Lung Model to Fine and Ultrafine Particles of Incinerator Fly Ash at the Air-liquid Interface

ATLA, Issue 36, pp. 285-298, 2008 Authors Silvia Diabaté, Sonja Mülhopt, Hanns-Rudolf Paur and Harald F. Krug Forschungszentrum Karlsruhe, Hermann-von-Helmholtz-Platz […]

March 10, 2008

Exposure of a multi-cellular in vitro model of human airway tissue to the whole cigarette smoke

Vol 177 (Abstracts Issue): pA728 (2008) Authors Walsh, P.T., Chalupowicz, D.G., Frankowski, R., Barnette, M. Discovery Biology, Respiratory CEDD, GlaxoSmithKline, […]

March 10, 2008

Cellular responses of primary human bronchial epithelial cells to whole cigarette smoke exposure

Vol 177 (Abstracts Issue): pA199 (2008) Authors Chalupowicz, D.G., Frankowski, R., Sanchez, Y., Kou, J., Barnette, M., and Walsh, P.T. […]

October 31, 2007

In Vitro Testing of Inhalable Fly Ash at the Air Liquid Interface

October 2007, pp 402-414 Authors Sonja Mülhopt, Hanns-Rudolf Paur, Silvia Diabaté and Harald F. Krug Forschungszentrum Karlsruhe, Hermann-von-Helmholtz-Platz 1, 76344, […]

October 7, 2007

Toxicological investigation of nanoparticles – effects on human cells

October 7-10, 2007 Authors Letizia Farmer, Alexander Graff, Sandra Szameit, Eva Valic, Helga Tuschl Austrian Research Centers GmbH – ARC, […]

July 23, 2007

A modified Ames assay reveals the mutagenicity of native cigarette mainstream smoke and its gas vapour phase

Experimental and Toxicologic Pathology 58 (2007) 383-392 Authors Michaela Aufderheide, Helga Gressmann Department of In-Vitro Toxicology, Fraunhofer Institute of Toxicology […]

March 23, 2007

Responses of differentiated primary human lung epithelial cells to exposure to diesel exhaust at an air-liquid interface

33:1, 27 – 51, 2007 Authors JeanClare Seagrave, Sandy Dunaway, Jacob D. McDonald, and Joe L. Mauderly Lovelace Respiratory Research […]

March 23, 2007

Cellular Mechanisms of Mainstream Cigarette Smoke-Induced Lung Epithelial Tight Junction Permeability Changes In Vitro

Inhalation Toxicology, 19:13–22, 2007 Authors Dorian S. Olivera Program in Toxicology, College of Pharmacy, University of New Mexico Health Sciences […]

December 31, 2006

Set-up of a dynamic in vitro exposure device for the study of indoor air pollutant effects on human derived cells

Vol 10, 2006 Authors F. Pariselli, M. G. Sacco & D. Rembges European Commission, Joint Research Centre, Institute for Health […]

December 31, 2006

Dynamic in-vitro Exposure of Human Derived Cells to Indoor Priority Pollutants

Report EUR 22285 EN, 2006 Authors F. Pariselli, M. G. Sacco, D. Rembges Institute for Health and Consumer Protection, Physical […]

October 31, 2005

Exposure System for Bioassays Measurement of the Toxicity of Airborne Nanoparticles

Authors Dr. Paur, S. Mülhopt and Dr. Diabate The exposure of human lung cells towards nano particles the correlation […]

April 25, 2005

Experimental Assessment of the Toxicological Effects of Inhaled Complex Mixtures on the Respiratory System – Feasibility and Limitations

Exp Toxic Pathol 2005, Supplement issued July, 2005 Workshop 23 – 25 April, 2005 in Barcelona, Spain In this Workshop […]

« Previous 1 2 3 4 Next »