Characterisation of a Vitrocell® VC 10 in vitro smoke exposure system using dose tools and biological analysis

September 3, 2013

doi:10.1186/1752-153X-7-146

Authors
David Thorne1, Joanne Kilford2, Rebecca Payne2, Jason Adamson1, Ken Scott1, Annette Dalrymple1, Clive Meredith1 and Deborah Dillon1

1 British American Tobacco, Group R&D, Southampton, United Kingdom
2 Covance Laboratories Ltd, Harrogate, North Yorkshire, United Kingdom

 

The study demonstrated that the VC 10® can produce stable tobacco smoke dilutions by particulate deposition, measured vapour phase, smoke marker delivery and biological responses from two independent in vitro test systems. 

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