News & Publications

March 16, 2025

Acute Toxicity of 1,3-Butadiene Exposure at the Air-Liquid Interface of Human Bronchial Epithelial Cells

Poster, SOT 64th Annual Meeting and ToxExpo, March 16–20, 2025, Orlando, Florida. Breandon Taylor1, Alexandra Noël2, Daniel Conklin1, and Sanjay […]

March 16, 2025

Characterization of the Aerosol Dose Uniformity in the 56-well Vitrocell® 48-2.0 Plus Exposure Module

Poster, SOT 64th Annual Meeting and ToxExpo, March 16–20, 2025, Orlando, Florida. Authors; M. J. Scian1, L. E. McFadden1, C.M. […]

March 16, 2025

Toxicity assessment of PM2.5 brake wear emissions using aerosol-based exposure models with A549-HMEC cell co-culture

Poster, SOT 64th Annual Meeting and ToxExpo, March 16–20, 2025, Orlando, Florida. Preliminary test of toxicological responce of brake wear […]

February 24, 2025

Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model

https://doi.org/10.1002/em.70000 Yuan Le1, Baiping Ren1, Levan Muskhelishvili2, Kelly Davis2, Yiying Wang1, William Gwinn3, Diego Rua4, Robert H. Heflich1, Xuefei Cao11Division […]

February 11, 2025

Evaluation of the toxicity of combustion smokes at the air-liquid interface: a comparison between two lung cell models and two exposure methods

DOI: 10.1007/s00204-025-03964-x A Ashrin 1, E Anna 1, E Peyret 1, G Barbier 1, Maxime Floreani 1, C Pointart 2, […]

January 24, 2025

Regulatory authorities recommend VITROCELL Modules for skin exposure to volatile chemicals and liquids

The Science Advisory Committee on Chemicals (SACC) of the US Environmental Protection Agency (EPA) has recently recommended the VITROCELL Skin […]

January 2, 2025

Research review and transcriptomic insights into Benzalkonium Chloride inhalation and disease association

https://doi.org/10.1016/j.ecoenv.2024.117610 Jun Woo Kim a, Min Seok Kim a, Ha Ryong Kim ba Center for Respiratory Safety Research, Korea Institute […]

January 2, 2025

Toxicological effects of long-term continuous exposure to ambient air on human bronchial epithelial Calu-3 cells exposed at the air-liquid interface

https://doi.org/10.1016/j.envres.2025.120759 E.J. Zimmermann a b, A. Das a b, A. Huber a b, N. Gawlitta a, E. Kuhn a, C. […]

December 17, 2024

Application of the market-ready NAVETTA electrodeposition chamber for controlled in vitro exposure with nano-scaled aerosols

https://doi.org/10.1016/j.csbj.2024.12.008 Magdalena Weiss a, Benjamin Punz a, Jo Van Laer b, An Jacobs b, Sylvie Remy b, Lisa Kleon a, […]

November 27, 2024

Peer Review of the 2024 Draft Risk Evaluation for 1,1-Dichloroethane and Draft Human Health Hazard Assessment for 1,2-Dichloroethane

Science Advisory Committee on Chemicals MeetingSeptember 17 to 19, 2024 Docket (EPA-HQ-OPPT-2024-0114) Alie Muneer A Set of Scientific Issues Being […]

October 22, 2024

Press Release: Collaborative Breakthrough in Lung-on-Chip Technology

Collaborative Breakthrough in Lung-on-Chip Technology: AlveoliX, VITROCELL, University of Bern and Helmholtz Institute for Pharmaceutical Research Saarland Drive Advances in […]

October 17, 2024

Quantitative AOP modeling of mucus hypersecretion using 3D cells for comparative risk estimation of heated tobacco product andcombustible cigarette

CORESTA Congress, 13-17 October 2024, Edinburgh, Scotland – UK Shigeaki Ito, Sakuya Ichikawa, Kazuo Erami, Akina Mori, Shugo Muratani, Keigo […]

October 17, 2024

Validation of the Vitrocell® 48 2.0+ 24-well mammalian module for assessing cigarettes and eHTPs: Evaluation of dilution airflow, dose resolution and 3D tissue suitability

CORESTA Congress, 13-17 October 2024, Edinburgh, Scotland – UK A. Seymour, R. Bedford and M. Hollings;Labcorp, Harrogate, UK AbstractThe use […]

October 17, 2024

Multiparameter characterisation of human alveolar macrophage-epithelial co-culture (ImmuLUNG) following exposure to whole smoke

CORESTA Congress, 13-17 October 2024, Edinburgh, Scotland – UK M. Hollings1, E. Rothwell1, R. Bedford1, N. Haydare2, B. Ghiot2, L. […]

October 17, 2024

Advancing Hazard Assessment Studies: Utilizing Inhalation on Chip Platform for Tobacco Product Evaluation

CORESTA Congress, 13-17 October 2024, Edinburgh, Scotland – UK ALEXIS in collaboration with Alveolix and Vitrocell ObjectiveThe goal of this […]

September 19, 2024

Evaluation of the local tolerance of flagellin aerosol therapy (FLAMOD) on primary human cell-based 3D in vitro nasal, bronchial, small-airway and alveolar models

AIT – Association of Inhalation Toxicology, 17.-19.September 2024, Cleveland, Ohio, USA Mireille Caul-Futy1, Cindia Ferreira1, Christine Caul-Futy2, Rosy Bonfante1, Itziar […]

September 19, 2024

The chemical composition of secondary organic aerosols regulates transcriptomic and metabolomic signaling in an epithelial-endothelial in vitro coculture

https://doi.org/10.1186/s12989-024-00600-x Svenja Offer1,2, Sebastiano Di Bucchianico1,2,3, Hendryk Czech1,2, Michal Pardo4, Jana Pantzke1,2, Christoph Bisig1, Eric Schneider2,3, Stefanie Bauer1, Elias J. […]

September 11, 2024

Comparison of Nickel Toxicity in Air-Liquid Interface Models of Human and Rat Bronchial Epithelial Cells

EUROTOX 08.-11.September 2024, Copenhagen, Denmark Samuel Buxton1, Maria Kloukinioti2, Mariska Grollers-Mulderij2, Evert Duistermaat3, Peter Tromp2, Frederique van Acker3, Adriana Oller4, […]

September 11, 2024

Testing Nanomaterials In Complex 3D In Vitro Lung Models

EUROTOX 08.-11.September 2024, Copenhagen, Denmark Emma Arnesdotter1, Pamina Weber1, Charlotte Stoffels1, Sebastian Klein1, Ionel Fizeşan2, Sebastien Cambier1, Elisa Moschini1,3, Tommaso […]

September 11, 2024

Development of an in vitro model of Dry Nose

EUROTOX 08.-11.September 2024, Copenhagen, Denmark Xiao-Yann Huang, Jimmy Vernaz, Song Huang and Samuel ConstantEpithelix Sàrl, 18 chemin des Aulx, CH-1228 […]

August 15, 2024

Comparison of the neurotoxic potency of different ultrafine particle fractions from diesel engine exhaust following direct and simulated inhalation exposure

https://doi.org/10.1016/j.scitotenv.2024.175469 Lora-Sophie Gerber a b, Dirk C.A. de Leijer a, Andrea Rujas Arranz a, Jonas M.M.L. Lehmann a b, Meike […]

August 3, 2024

A stretchable human lung-on-chip model of alveolar inflammation for evaluating anti-inflammatory drug response

July 26, 2024

Toxicological evaluation of primary particulate matter emitted from combustion of aviation fuel

https://doi.org/10.1016/j.chemosphere.2024.142958 Gloria Melzi a, Jos van Triel b, Eliot Durand c, Andrew Crayford c, Ismael K. Ortega d, Rafael Barrellon-Vernay […]

July 20, 2024

An original device to assess the respiratory impact of indoor air VOCs mixture using an in vitro approach

https://doi.org/10.1016/j.indenv.2024.100037 Plaisance Hervéa, Costarramone Nathaliea, Dalliès Gaëllea, Al Zallouha Marguerittab, Achard Sophieb, Desauziers Valérieaa IPREM, IMT Mines Ales, Université de […]

News & Publications

Acute Toxicity of 1,3-Butadiene Exposure at the Air-Liquid Interface of Human Bronchial Epithelial Cells

Characterization of the Aerosol Dose Uniformity in the 56-well Vitrocell® 48-2.0 Plus Exposure Module

Toxicity assessment of PM2.5 brake wear emissions using aerosol-based exposure models with A549-HMEC cell co-culture

Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model

Evaluation of the toxicity of combustion smokes at the air-liquid interface: a comparison between two lung cell models and two exposure methods

Regulatory authorities recommend VITROCELL Modules for skin exposure to volatile chemicals and liquids

Research review and transcriptomic insights into Benzalkonium Chloride inhalation and disease association

Toxicological effects of long-term continuous exposure to ambient air on human bronchial epithelial Calu-3 cells exposed at the air-liquid interface

Application of the market-ready NAVETTA electrodeposition chamber for controlled in vitro exposure with nano-scaled aerosols

Peer Review of the 2024 Draft Risk Evaluation for 1,1-Dichloroethane and Draft Human Health Hazard Assessment for 1,2-Dichloroethane

Press Release: Collaborative Breakthrough in Lung-on-Chip Technology

Quantitative AOP modeling of mucus hypersecretion using 3D cells for comparative risk estimation of heated tobacco product andcombustible cigarette

Validation of the Vitrocell® 48 2.0+ 24-well mammalian module for assessing cigarettes and eHTPs: Evaluation of dilution airflow, dose resolution and 3D tissue suitability

Multiparameter characterisation of human alveolar macrophage-epithelial co-culture (ImmuLUNG) following exposure to whole smoke

Advancing Hazard Assessment Studies: Utilizing Inhalation on Chip Platform for Tobacco Product Evaluation

Evaluation of the local tolerance of flagellin aerosol therapy (FLAMOD) on primary human cell-based 3D in vitro nasal, bronchial, small-airway and alveolar models

The chemical composition of secondary organic aerosols regulates transcriptomic and metabolomic signaling in an epithelial-endothelial in vitro coculture

Comparison of Nickel Toxicity in Air-Liquid Interface Models of Human and Rat Bronchial Epithelial Cells

Testing Nanomaterials In Complex 3D In Vitro Lung Models

Development of an in vitro model of Dry Nose

Comparison of the neurotoxic potency of different ultrafine particle fractions from diesel engine exhaust following direct and simulated inhalation exposure

A stretchable human lung-on-chip model of alveolar inflammation for evaluating anti-inflammatory drug response

Toxicological evaluation of primary particulate matter emitted from combustion of aviation fuel

An original device to assess the respiratory impact of indoor air VOCs mixture using an in vitro approach

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