Module for the direct exposure of skin tissue to liquid aerosols.
This system is specifically designed for dose-controlled and spatially uniform deposition of liquid aerosols on skin samples. The aerosol is applied for a short time of approx. 3-4 minutes.
The base module is made of electropolished stainless steel. It has an electronically controlled heating unit. The Cloud aerosol chamber is made of polycarbonate.
VITROCELL® offers 2 options for aerosol generation:
Nebulizers for larger particle sizes are available upon request.
The VITROCELL® Cloud can be used for aerosols generated from liquids and suspensions. Possible fields of application include toxicity testing including nanoparticle suspensions.
The unique tissue holders have been specifically designed to enable tight and reliable skin fixation. This module is a legitimate and superior alternative to Franz cells.
The skin module is used specifically for samples with smaller surfaces of approx. 1 cm2. Specifically designed holders ensure a tight and reliable fixation of skin samples.
Alternatively, cell culture inserts may be used.
The specifically designed extraction tools ensure precision removal of the tissue holders.
The system comes with a choice of 3 types of vibrating mesh nebulizers having droplet MMAD ranges of 2.5 – 6.0 µm, 2.5 – 4.0 µm and 4.0 – 6.0 µm.
Recommended nebulisation volumes are 200 µl. So the device is particularly suitable for testing whenever small quantities of testing materials are available.