Application Areas

for in vitro exposure devices


Human Health Risk Assessment

Leading research institutes, contract research organisations, regulatory authorities as well as pharmaceutical and other industries throughout the world use our turnkey exposure systems in manifold applications for state-of-the-art health risk assessment.

Without Use of Animals

It is becoming increasingly important to accurately characterize the biological activities of active substances and mixtures in the respiratory system without the use of animals: here we provide the most advanced, application-oriented technology and worldwide leading product solutions.

Application Areas for in vitro Inhalation

Environmental Health
  • Air quality monitoring: Assessment of indoor and outdoor pollutants with long-term sampling >24 h
  • Occupational health: Workplace exposure
  • Public health: Pollution in urban areas

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Pharmaceutical Evaluation
  • Drug development for respiratory diseases:
    Assessment of inhalable therapeutics
  • Drug delivery via liquid or dry powder aerosols
  • Nanomedicine and advanced therapies

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Tobacco and  E-Cigarette Testing
  • Safety assessment: Toxicity profiling
  • Product development and comparison
  • Regulatory compliance
  • Harm reduction assessment

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Nanomaterial Safety
  • Safety and risk assessment: Toxicity profiling
  • Occupational safety: Workplace exposure
  • Consumer product safety: Regulatory compliance, product testing

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Bacteria and  Virus Research
  • Bacterial and viral pathogenesis
  • Antiviral drug testing on airway tissues
  • Inhalable vaccine development and evaluation
  • Transmission studies: Aerosol stability

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Chemicals  and Pesticides
  • Hazard identification: Dose–response assessment
  • Regulatory compliance
  • Environmental and occupational safety

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Cosmetics
  • Ingredient safety assessment: Toxicity profiling, respiratory sensitizers or allergenicity testing
  • Occupational and manufacturing safety
  • Regulatory compliance under 3R strategy

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Videos

VITROCELL Exposure Systems for in vitro Inhalation Toxicology

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