Comparison of the bacterial mutagenicity of mainstream whole smoke from cigarettes with different levels of menthol

March 10, 2011

March 06-10, 2011

Robert D. Leverette

Life Sciences, A. W. Spears Research Center, Lorillard Tobacco Company, Greensboro, NC 27405, USA


This study was conducted to compare the mutagenicity of mainstream whole-smoke and wet total particulate matter from two sets of experimental cigarettes to determine if menthol has an effect on this endpoint. All cigarettes were smoked under ISO on a VITROCELL® VC10 smoking robot. TA98 and TA100 were exposed in the VITROCELL® Ames exposure modules.

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