An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

July 26, 2013


Sebastian G Klein12, Tommaso Serchi1, Lucien Hoffmann1, Brunhilde Blömeke2 and Arno C Gutleb1*

1 Department Environment and Agro-biotechnologies (EVA), Centre de Recherche Public – Gabriel Lippmann, 41 rue du Brill, L-4422 Belvaux, Luxembourg
2 Department of Environmental Toxicology, University of Trier, Universitätsring 15, Trier, Germany


Exposition of fine and ultra-fine particles on a tetraculture of A549, TPA-1, HCM-1 and EA.hy 926 cells to measure oxidative stress with the IL-8 and DCFH-DA assay.

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