Application of a modified gaseous exposure system to the in vitro toxicological assessment of tobacco smoke toxicants

June 2, 2014

Volume 55, Issue 8, Article first published online: 2 JUN 2014 (doi: 10.1002/em.21876)

Damien Breheny1, Fiona Cunningham1, Joanne Kilford2, Rebecca Payne2, Deborah Dillon1 and Clive Meredith1

1 British American Tobacco, Group R&D, Southampton, Hampshire, United Kingdom
2 Covance Laboratories Ltd, North Yorkshire, United Kingdom

Demonstration of the suitability of the VC 10® exposure system for the assesment of the mutagenic potential of gases using the AMES Assay. Not only cigarette smoke, also a wide range of gaseous compounds and aerosol mixtures can be studied.

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