Optimization of the VITROCELL® Exposure System for in vitro toxicity testing of diesel emissions at the air-liquid interface

February 6, 2013

February 5-6, 2013

Rebecca Greenan1, Tak Chan2, Mathias Könczöl3, Julie Bourdon1, Debbie Rosenblatt2, Marie-Josée Poitras2and Paul A. White1

1 Mechanistic Studies Division, Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada
2 Emissions Research and Measurement Section, Environment Canada, Ottawa, ON, Canada
3 Department of Pharmaceutical Biology and Biotechnology, University of Freiburg, Germany


Exposition of emissions from different diesel blends on A549 cells with endpoints for genotoxicity (WST-1, NRU, Caspase III/VII) and oxidative stress (TBARS).

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