March 23-25, 2010
Richard Gminski, Christoph Modest, Benedikt Armbruster, Tao Tang, Mathias Könczöl, Volker Mersch-Sundermann
Department of Environmental Health Sciences Institute of Environmental Medicine and Hospital Hygiene (IUK), Freiburg University Medical Centre / Germany
To develop a new bioassay for the air-liquid interface system, they optimized the conditions for the cytochalasin-block in vitro micronucleus test procedure using commercially available PTFE cell culture inserts. After exposure, cells were evaluated for cell viability (WST-1 assay) and for the induction of micronuclei.