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Page 5
News & Publications
August 31, 2011
VITROCELL® Bio Aerosol Generator for use in turnkey in vitro exposure systems
An aerosol generator for smaller quantities of test aerosol operating at lower air flows. The solution for aerosol generator whenever […]
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August 25, 2011
A novel approach to assess irritant or respiratory allergenic potential of chemicals in vitro
August 21-25, 2011 Authors Singal M.1, Vitale D.1, Smith L.1, Czollner K.2, Farmer L.2, Höpfner C.2, Satzer H-P.2, Schoeffmann S.2, […]
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August 22, 2011
Prävalidierungsstudie zur Prüfung der toxischen Wirkung von inhalativ wirksamen Stoffen (Gase)
1. Auflage. Dortmund: Bundesanstalt für Arbeitsschutz und Arbeitsmedizin 2011 Authors G. Linsel, M. Bauer, E. Berger-Preiß, C. Gräbsch, H. Kock, […]
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August 12, 2011
Ex vivo toxicity of nitrogen dioxide in human nasal epithelium at the WHO defined 1-h limit value
2011 Nov 10;207(1):89-95. doi: 10.1016/j.toxlet.2011.08.004. [Epub ahead of print] Authors C. Koehler, C. Ginzkey, G. Friehs, S. Hackenberg, K. Froelich, […]
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August 5, 2011
Sequential air-liquid exposure of human respiratory cells to chemical and biological pollutants
2011 Nov 10;207(1):53-9. doi: 10.1016/j.toxlet.2011.07.028 [Epub ahead of print] Authors Persoz C, Leleu C., Achard S., Fasseu M., Menotti J., […]
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March 31, 2011
VITROCELL® Skin Exposure System for Tissue
The new system is made of stainless steel. It has integrated magnetic stirrers and a central heating via water circuit. […]
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March 10, 2011
Comparison of the bacterial mutagenicity of mainstream whole smoke from cigarettes with different levels of menthol
March 06-10, 2011 Authors Robert D. Leverette Life Sciences, A. W. Spears Research Center, Lorillard Tobacco Company, Greensboro, NC 27405, […]
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March 10, 2011
In vitro exposure of organotypical 3D epithelial tissues to cigarette smoke as a potential alternative to rodent inhalation studies
March 06-10, 2011 Authors Weisensee, D., Kurkowsky, B., Hebestreit, M., Wagner, S. and Schueller J. Philip Morris Research Laboratories GmbH, Cologne, […]
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July 30, 2010
New on IUTOX
The ideal tool for monitoring of partcle deposition in the exposure module. This dose monitoring tool is a milestone in […]
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July 30, 2010
New on IUTOX
The new tool to produce gas mixtures in the ppb range. When gas mixtures are not available in cylinders, because […]
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July 23, 2010
Toxicological investigation of laser printer emissions – Effects on human cells
July 16-23, 2010 Authors Tao Tang, Richard Gminski, Rebecca Kuhn, Mathias Könczöl, Carsten Gründemann, Benedikt Armbruster, Volker Mersch-Sundermann Institute of […]
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July 20, 2010
Untersuchungen zur genetischen Toxizität von Emissionen aus Laserdruckern in A549-Zellen im Vitrocell®-Transwell-Expositionssystem
Authors Tao Tang, Richard Gminski und Volker Mersch-Sundermann Department of Environmental Health Sciences, Institute of Environmental Medicine and Hospital Hygiene […]
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June 30, 2010
Effects of acute in vitro exposure of murine precision-cut lung slices to gaseous nitrogen dioxide and ozone in an air-liquid interface (ALI) culture
2010 Jul 1;196(2):117-24. doi: 10.1016/j.toxlet.2010.04.004. [epub ahead of print] Authors S. Switalla, J. Knebel, D. Ritter, N. Krug, A. Braun, […]
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March 31, 2010
Cytotoxicity and genotoxicity in human lung epithelial A549 cells caused by airborne volatile organic compounds emitted from pine wood and oriented strand boards
2010 Jun 16;196(1):33-41. doi: 10.1016/j.toxlet.2010.03.015. [epub ahead of print] Authors Gminski R, Tang T, Mersch-Sundermann V. Institute of Environmental Medicine […]
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March 31, 2010
SOT Meeting Salt Lake City, USA
VITROCELL® presented advanced solutions for the exposure of cells to airborne nano particles, gases and complex mixtures at the 2010 […]
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March 25, 2010
A novel in vitro micronucleus (MN) test procedure after exposure of human derived lung cells to volatile chemicals at the air/liquid interface in vitro
March 23-25, 2010 Authors Richard Gminski, Christoph Modest, Benedikt Armbruster, Tao Tang, Mathias Könczöl, Volker Mersch-Sundermann Department of Environmental Health […]
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March 10, 2010
An in vitro model to evaluate the inflammatory response after gaseous formaldehyde exposure of lung epithelial cells
2010 Jun 2;195(2-3):99-105. doi: 10.1016/j.toxlet.2010.03.003. [epub ahead of print] Authors Persoz C., Achard S., Leleu C., Momas I., Seta N. […]
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March 7, 2010
Aspects of nitrogen dioxide toxicity in environmental urban concentrations in human nasal epithelium.
2010 Jun 1;245(2):219-25. doi: 10.1016/j.taap.2010.03.003. [Epub ahead of print] Authors Koehler C., Ginzkey C., Friehs G., Hackenberg S., Froelich K., […]
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March 3, 2010
Evaluation of Dicarbonyls Generated in a Simulated Indoor Air Environment Using an in Vitro Exposure System
2010 Jun;115(2):453-61. doi: 10.1093/toxsci/kfq067. [Epub ahead of print] Authors Anderson SE, Jackson LG, Franko J., Wells JR. National Institute for […]
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January 14, 2010
A biological test for environmental toxins
Highlights from Baden-Württemberg, January 14, 2010 Authors Dr. rer. nat. Richard Gminski Institute of Environmental Medicine and Hospital Hygiene (IUK), […]
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September 16, 2009
Cytokine Production after Acute Exposure of Precision Cut Lung Slices to NO2 and O3
September 13-16, 2009 Authors K. Sewald, S. Switalla, D. Ritter, N. Krug, J. Knebel, A. Braun Fraunhofer Institute for Toxicology […]
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September 16, 2009
An in vitro model to assess the impact on respiratory cells (A549) of air pollution
September 13-16, 2009. Bo Holmstedt Authors Charles Persoz, Sophie Achard, Christopher Leleu, Isabelle Momas, Nathalie Seta Laboratoire Sante Publique et […]
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September 11, 2009
Biological effects in human lung cells exposed to platinum nanoparticle aerosol
September 06-11, 2009 Authors S. Diabaté, C. Weiss, S. Mülhopt, H.-R. Paur, V. Niedetzky, M. Seipenbusch Institute for Toxicology and […]
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September 11, 2009
Toxic effects of nanoparticles from biomass combustion
September 06-11, 2009 Authors Werner Fr. Dreher, Frank Weise, Karen Böhme, Steffen Lutz, Michael Struschka, Johannes Brodbeck, Sonja Mülhopt, Hanns-Rudolf […]
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September 11, 2009
The QCM – Online Dose Measurement with high relative Humidity
September 06-11, 2009 Authors S. Mülhopt, A. Comouth, A. Grotz, T. Krebs, H.-R. Paur Institute for Technical Chemistry, Thermal Waste […]
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September 3, 2009
Air/Liquid Culture and Exposure Technique: Preliminary Results of a Prevalidation Study
August 30 – September 3, 2009 Authors Smirnova, L.1, Liebsch, M.1, Tharmann, J.1, Pirow, R.1, Luch, A.1, Bauer, M.2, Graebsch, […]
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August 31, 2009
SOT Meeting Baltimore
VITROCELL® presented turnkey in vitro test systems for nano particles, gases and complex mixtures at the 2009 SOT Annual Meeting […]
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August 31, 2009
WC 7 Rome
VITROCELL® presents key technologies for the in vitro exposure of airborne substances such as gases, complex mixtures, nano particles and […]
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March 23, 2009
Lung toxicity determination by in vitro exposure at the air-liquid interface with an integrated online dose measurement
Journal of Physics: Conference Series 170 (2009) 012008 (doi:10.1088/1742-6596/170/1/012008) Authors Sonja Mülhopt, S. Diabaté, T. Krebs, C. Weiss and H.-R. […]
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March 19, 2009
Identification of Indoor Air Contaminants Using an in Vitro Exposure System
March 15-19, 2009 Authors Laurel G. Jackson, J. R. Wells, Jason Ham, Albert Munson, and Stacey E. Anderson National Institute […]
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October 31, 2008
EUROTOX
The VITROCELL® in vitro test systems for the analysis of the effects of nanoparticles and airborne pollutants found strong interest […]
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October 8, 2008
Online dose determination for in vitro experiments with nano particles in the Karlsruhe Exposure System
October 5-8, 2008 Authors S. Mülhopt, H.-R. Paur, T. Krebs Forschungszentrum Karlsruhe, Eggenstein – Leopoldshafen, Germany VITROCELL Systems GmbH, Waldkirch, […]
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August 6, 2008
News Release
The new development opens up advanced possibilities for research. The smoking machine VITROCELL® VC10® CHEMCONTROL is specially developed for chemical […]
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March 30, 2008
SOT Meeting Seattle
VITROCELL presents the direct exposure technology for the in vitro analysis of airborne substances such as gases, nano particles and […]
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March 10, 2008
The Response of a Co-culture Lung Model to Fine and Ultrafine Particles of Incinerator Fly Ash at the Air-liquid Interface
ATLA, Issue 36, pp. 285-298, 2008 Authors Silvia Diabaté, Sonja Mülhopt, Hanns-Rudolf Paur and Harald F. Krug Forschungszentrum Karlsruhe, Hermann-von-Helmholtz-Platz […]
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March 10, 2008
Exposure of a multi-cellular in vitro model of human airway tissue to the whole cigarette smoke
Vol 177 (Abstracts Issue): pA728 (2008) Authors Walsh, P.T., Chalupowicz, D.G., Frankowski, R., Barnette, M. Discovery Biology, Respiratory CEDD, GlaxoSmithKline, […]
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March 10, 2008
Cellular responses of primary human bronchial epithelial cells to whole cigarette smoke exposure
Vol 177 (Abstracts Issue): pA199 (2008) Authors Chalupowicz, D.G., Frankowski, R., Sanchez, Y., Kou, J., Barnette, M., and Walsh, P.T. […]
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October 31, 2007
In Vitro Testing of Inhalable Fly Ash at the Air Liquid Interface
October 2007, pp 402-414 Authors Sonja Mülhopt, Hanns-Rudolf Paur, Silvia Diabaté and Harald F. Krug Forschungszentrum Karlsruhe, Hermann-von-Helmholtz-Platz 1, 76344, […]
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October 8, 2007
EUROTOX Congress
VITROCELL® SYSTEMS presents new equipment developments for in vitro inhalation toxicology at the EUROTOX 2007 (44th Congress of the European […]
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October 7, 2007
Toxicological investigation of nanoparticles – effects on human cells
October 7-10, 2007 Authors Letizia Farmer, Alexander Graff, Sandra Szameit, Eva Valic, Helga Tuschl Austrian Research Centers GmbH – ARC, […]
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September 8, 2007
News Release
Approximately 1.000 scientists from all over the world met in Tokyo to exchange their views on the latest developments on […]
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July 23, 2007
A modified Ames assay reveals the mutagenicity of native cigarette mainstream smoke and its gas vapour phase
Experimental and Toxicologic Pathology 58 (2007) 383-392 Authors Michaela Aufderheide, Helga Gressmann Department of In-Vitro Toxicology, Fraunhofer Institute of Toxicology […]
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March 23, 2007
Responses of differentiated primary human lung epithelial cells to exposure to diesel exhaust at an air-liquid interface
33:1, 27 – 51, 2007 Authors JeanClare Seagrave, Sandy Dunaway, Jacob D. McDonald, and Joe L. Mauderly Lovelace Respiratory Research […]
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March 23, 2007
Cellular Mechanisms of Mainstream Cigarette Smoke-Induced Lung Epithelial Tight Junction Permeability Changes In Vitro
Inhalation Toxicology, 19:13–22, 2007 Authors Dorian S. Olivera Program in Toxicology, College of Pharmacy, University of New Mexico Health Sciences […]
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March 20, 2007
News Release
The new exposure system is a benchmark for in vitro research with higher throughput. It offers up to 6 doses […]
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March 20, 2007
News Release
The new exposure module for inserts in the 12-well size offers high durability due to construction in stainless steel. The […]
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December 31, 2006
Set-up of a dynamic in vitro exposure device for the study of indoor air pollutant effects on human derived cells
Vol 10, 2006 Authors F. Pariselli, M. G. Sacco & D. Rembges European Commission, Joint Research Centre, Institute for Health […]
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December 31, 2006
Dynamic in-vitro Exposure of Human Derived Cells to Indoor Priority Pollutants
Report EUR 22285 EN, 2006 Authors F. Pariselli, M. G. Sacco, D. Rembges Institute for Health and Consumer Protection, Physical […]
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October 31, 2005
Exposure System for Bioassays Measurement of the Toxicity of Airborne Nanoparticles
Authors Dr. Paur, S. Mülhopt and Dr. Diabate The exposure of human lung cells towards nano particles the correlation […]
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April 25, 2005
Experimental Assessment of the Toxicological Effects of Inhaled Complex Mixtures on the Respiratory System – Feasibility and Limitations
Exp Toxic Pathol 2005, Supplement issued July, 2005 Workshop 23 – 25 April, 2005 in Barcelona, Spain In this Workshop […]
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December 31, 2004
Comparative Assessment of Toxicities of Mainstream Smoke from Commercial Cigarettes
Inhalation Toxicology 16:1-10, 2004 Authors Detlef Ritter, Jan W. Knebel, and Michaela Aufderheide Online monitoring of generated smoke aerosols […]
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December 31, 2004
A modified CULTEX® system for the direct exposure of bacteria to inhalable substances
Exp Toxic Pathol 2004; 55: 451-454 Authors Michaela Aufderheide and Ulrich Mohr Establishment of a novel experimental approach using […]
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December 31, 2003
Novel approaches for studying pulmonary toxicity on vitro
ELSEVIER, 140-141 (2003) 205-211 Authors Michaela Aufderheide, Jan W. Knebel, Detlef Ritter The goal of this studiy is to […]
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June 30, 2003
In Vitro Tests for Gases and Aerosols – an Alternative Step into the Future
Authors Prof. Dr. Michaela Aufderheide This News Report presents the screening method with the modular exposure unit, that can […]
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March 30, 2003
Exposure of human lung cells to inhalable substances
Inhalation Toxicology, 15:67-84, 2003 Authors Detlef Ritter, Jan W. Knebel, Michaela Aufderheide The experimental setup included online monitoring of […]
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February 25, 2003
An improved in vitro model for testing the pulmonary toxicity of complex mixtures such as cigarette smoke
Exp Toxic Pathol 2003; 55: 51-57 Authors Michaela Aufderheide, Jan W. Knebel, and Detlef Ritter The study presented a […]
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December 31, 2002
A Method for the In Vitro Exposure of Human Cells to Environmental and Complex Gaseous Mixtures: Application to Various Types of Atmosphere
Issue 30, pp. 433-441, 2002 Authors Michaela Aufderheide, Jan W. Knebel and Detlef Ritter This study presents the testing […]
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June 30, 2002
In vitro genotoxicity assay of sidestream smoke using a human bronchial epithelial cell line
Volume 40, Issue 6, pp. 845-850, June, 2002 Authors L. Wolz, G. Krause, G. Scherer, M. Aufderheide, U. Mohr […]
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April 30, 2002
Exposure of human lung cells to native diesel motor exhaust-development of an optimized in vitro test strategy
Volume 16, Issue 2, pp. 185-192, April, 2002 Authors J.W. Knebel, D. Ritter, M. Aufderheide The experimental set-up allows […]
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March 31, 2002
Responses of cultured lung epithelial cells to airborne diesel emissions
Paper issued March, 2002 Authors J. C. Seagrave, J. D. McDonald, and J. L. Mauderly Lovelace Respiratory Research Institute Investigation […]
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August 1, 2001
In vitro exposure of isolated cells to native gaseous compounds – Development and validation of an optimized system for human lung cells
Exp Toxic Pathol 2001; 53: 373-386 accepted August 2, 2001 Authors Detlef Ritter, Jan W. Knebel, and Michaela Aufderheide […]
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