News & Publications

September 26, 2022

Product News 06-9/2022

For fully automated and repeated row-by-row exposure of 12-, 24- and 96-well sized cell culture inserts. Testing of up to […]

September 9, 2022

ICT 2022 – International Congress of Toxicology

After an intensive preparation period, it is with great pleasure that the Dutch Society of Toxicology (NVT) is welcoming […]

August 22, 2022

Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways

https://doi.org/10.1038/s41598-022-18098-8 Torben Stermann1, Thach Nguyen1, Burkhard Stahlmecke2, Ana Maria Todea2, Selina Woeste1, Inken Hacheney1, Jean Krutmann1,3, Klaus Unfried1, Roel P. […]

July 29, 2022

Advanced Respiratory Models for Hazard Assessment of Nanomaterials—Performance of Mono-, Co- and Tricultures

https://doi.org/10.3390/nano12152609 Laura Maria Azzurra Camassa 1, Elisabeth Elje 2,3, Espen Mariussen 2,4, Eleonora Marta Longhin 2, Maria Dusinska 2, Shan […]

June 21, 2022

Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells

https://doi.org/10.1016/j.envint.2022.107366 Michal Pardoa, Svenja Offerbc, Elena Hartnerbc, Sebastiano Di Bucchianicob, Christoph Bisigb, Stefanie Bauerb, Jana Pantzkebc, Elias J. Zimmermannbc, XinCaobc, […]

June 15, 2022

Characterization of Aerosol Deliveries from Combustible Cigarettes, Heated Tobacco Products, and Electronic Nicotine Delivery Systems Using the Vitrocell Ames 48

DOI: 10.1089/aivt.2022.0001 Brian M. Keyser,1 Robert Leverette,1 Michael Hollings,2 Adam Seymour,2 Randy J. Weidman,3 Carlton J. Bequette,3 and Kristen Jordan1 […]

June 1, 2022

Product News 05-4/2022

For cell culture exposure to smallest quantities of dry powders The VITROCELL® PowderX allows for aerosolisation of small quantities of […]

April 15, 2022

Aerosol–Cell Exposure System Applied to Semi-Adherent Cells for Aerosolization of Lung Surfactant and Nanoparticles Followed by High Quality RNA Extraction

https://doi.org/10.3390/nano12081362 Mélanie M. Leroux 1 , Romain Hocquel 1, Kevin Bourge 1 , Boštjan Kokot 2 , Hana Kokot 2 […]

April 11, 2022

Product News 04-3/2022

Aerosol exposure for breathing AX Lung-on-Chip The VITROCELL® Cloud Alpha AX12 is our newest innovation in the Cloud family and […]

April 6, 2022

Product News 04-2/2022

Manual smoking machine with high tech features The VC 1 smoking machine is used for a controlled aerosol generation of […]

April 4, 2022

Product News 04-1/2022

Increase of nebulizations and evacuation of residual gaseous compounds A typical Cloud exposure allows 3 consecutive nebulizations. The PowerVent option […]

March 27, 2022

Nrf2 Responses of Commercial Cigarette Whole Smoke and Aerosol from Six Electronic Nicotine Delivery Systems (ENDS) in a 3D Human Airway Model

Brian M. Keyser1, John Wertman1, Michael Hollings2, Robert Bedford2, and Kristen Jordan1 1 Scientific & Regulatory Affairs, RAI Services Company, […]

March 27, 2022

Cytotoxicity Assessment of Electronic Nicotine Delivery Systems (ENDS) and Combustible Cigarette Aerosols Utilizing Standard and Whole Aerosol Exposure Approaches in the Neutral Red Uptake Assay

Robert Leverette1, Thomas Shutsky1, John Wertman1, Katarina Aleksa2, Dhatri Lakshmanan2, Rebecca Payne3, Kristen Jordan1 1Scientific & Regulatory Affairs, RAI Services […]

March 27, 2022

In Vitro Cytotoxicity Assessment of 3D Human Airway Tissue Following Exposure to Whole Aerosol/Smoke Generated from Electronic and Combustible Cigarettes

Thomas Shutsky1, Brian M. Keyser1, Kristen Jordan1, Michael Hollings2, and Emma Rothwell2 1Scientific & Regulatory Affairs, RAI Services Company, Winston-Salem, […]

March 22, 2022

Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium

https://doi.org/10.1172/jci.insight.155589 Kristine M. Abo,1,2 Julio Sainz de Aja,3,4,5 Jonathan Lindstrom-Vautrin,1 Konstantinos-Dionysios Alysandratos,1,2 Alexsia Richards,6 Carolina Garcia-de-Alba,3,4,5 Jessie Huang,1,2 Olivia T. […]

March 18, 2022

Fit-for-purpose characterization of air-liquid-interface (ALI) in vitro exposure systems for e-vapor aerosol

https://doi.org/10.1016/j.tiv.2022.105352 J. Zhang1, U. Doshi1, R.L. Wolz2, P. Kosachevsky2, M.J. Oldham1,2, I.G. Gillman2,2 , K.M. Lee1 1Altria Client Services LLC, […]

March 1, 2022

The priming effect of diesel exhaust on native pollen exposure at the air-liquid interface

https://doi.org/10.1016/j.envres.2022.112968 Joana Candeiasa, Elias J. Zimmermannbc, Christoph Bisigb, Nadine Gawlittabc, Sebastian Oederb, Thomas Grögerb, Ralf Zimmermannbc, Carsten B. Schmidt-Webera, Jeroen […]

February 7, 2022

Pulmonary Delivery of Aerosolized Chloroquine and Hydroxychloroquine to Treat COVID-19: In Vitro Experimentation to Human Dosing Predictions

Aditya R. Kolli, 1 Tanja Zivkovic Semren, 1 David Bovard, 1 Shoaib Majeed, 1 Marco van der Toorn, 1 Sophie […]

February 3, 2022

Product News 02-1/2022

For liquid droplet sizes 9 – 12 μm with diffusor Certain chemicals or formulations, for example nasal sprays, often have […]

February 3, 2022

Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air–Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs

https://doi.org/10.1289/EHP9413 Svenja Offer,1,2Elena Hartner,1,2Sebastiano Di Bucchianico,1Christoph Bisig,1Stefanie Bauer,1Jana Pantzke,1,2Elias J. Zimmermann,1,2Xin Cao,1,2Stefanie Binder,1,2Evelyn Kuhn,1Anja Huber,1Seongho Jeong,1,2Uwe Käfer,1,2Patrick Martens,2Arunas Mesceriakovas,3Jan Bendl,1,4,5Ramona […]

February 2, 2022

LIVe 2022 – Lung in vitro event for innovative & predictive models

Lung in vitro event for innovative & predictive models After a successful first edition in 2018, LIVe2022 is back in […]

February 2, 2022

MPS World Summit 2022

Connect, Exchange, Educate Microphysiological System (MPS): cell culture systems replicating (patho)physiology through engineered organ architecture and functionality. This includes especially […]

February 2, 2022

Smoking Machine VC 10 S-TYPE for Heat-not-Burn Tobacco Devices

Now Heated Tobacco Products (HTP) can be continuously smoked with automatic button actuation. The heat-and-turn feature for heat-not-burn devices enables […]

February 2, 2022

2022 International Particulate Toxicology Conference IPTC

The IPTC is one of the longest standing scientific meetings in its field. It started in the UK in 1979 […]

News & Publications

Product News 06-9/2022

ICT 2022 – International Congress of Toxicology

Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways

Advanced Respiratory Models for Hazard Assessment of Nanomaterials—Performance of Mono-, Co- and Tricultures

Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells

Characterization of Aerosol Deliveries from Combustible Cigarettes, Heated Tobacco Products, and Electronic Nicotine Delivery Systems Using the Vitrocell Ames 48

Product News 05-4/2022

Aerosol–Cell Exposure System Applied to Semi-Adherent Cells for Aerosolization of Lung Surfactant and Nanoparticles Followed by High Quality RNA Extraction

Product News 04-3/2022

Product News 04-2/2022

Product News 04-1/2022

Nrf2 Responses of Commercial Cigarette Whole Smoke and Aerosol from Six Electronic Nicotine Delivery Systems (ENDS) in a 3D Human Airway Model

Cytotoxicity Assessment of Electronic Nicotine Delivery Systems (ENDS) and Combustible Cigarette Aerosols Utilizing Standard and Whole Aerosol Exposure Approaches in the Neutral Red Uptake Assay

In Vitro Cytotoxicity Assessment of 3D Human Airway Tissue Following Exposure to Whole Aerosol/Smoke Generated from Electronic and Combustible Cigarettes

Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium

Fit-for-purpose characterization of air-liquid-interface (ALI) in vitro exposure systems for e-vapor aerosol

The priming effect of diesel exhaust on native pollen exposure at the air-liquid interface

Pulmonary Delivery of Aerosolized Chloroquine and Hydroxychloroquine to Treat COVID-19: In Vitro Experimentation to Human Dosing Predictions

Product News 02-1/2022

Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air–Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs

LIVe 2022 – Lung in vitro event for innovative & predictive models

MPS World Summit 2022

Smoking Machine VC 10 S-TYPE for Heat-not-Burn Tobacco Devices

2022 International Particulate Toxicology Conference IPTC

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