Following the VITROCELL® User Group Meeting 2018 in San Antonio, Texas, USA, international scientists from Europe, Japan, Korea and USA reconvened in March 2019.
The informal event organized into short presentations and posters was followed by open discussions. It was an excellent opportunity to discuss the latest developments of VITROCELL®, to exchange your experience in working with the equipment and to meet other fellow researchers.
The meeting took place prior to the international Society of Toxicology 58th Annual Meeting and ToxExpo, March 10 – 14, 2018, in Baltimore, USA - one of the largest international conferences related to toxicology.
Focus of the event was to share VITROCELL® activities since the last meeting, to exchange latest research results, to give an update on VITROCELL’s participation in major research programs as well as the presentation of new products for 2019.
Highlights were:
- Update on validation of the VITROCELL® 24/48 and AMES 48 exposure systems:
7 doses @ 6 replicates plus one clean air control @ 6 replicates.
- Versatile 5-channel linear smoking machine VITROCELL® VC 1 S-TYPE:
for chemical characterization and in vitro testing of electronic and combustion cigarettes as well as next generation products (NGP).
- VITROCELL® Powder Atomizer:
for aerosolization of dry powders
- Flow Control Software:
for setting and monitoring of flow controllers for dilution air flow
- New VITROCELL® Cloud Systems
VITROCELL® Cloud PowerVent and Cloud MAX:
for evacuation of residual gaseous compounds and nebulization of smallest volumes
- VITROCELL® Holder System for e-cigarettes:
Secure and tight connection of any puff-actuated device to Smoking Machine
- Media Inserts for VITROCELL® Exposure Modules 6 & 12 Series:
Easier maintenance
- Integration of the AlveoliX Lung-on-Chip into VITROCELL® exposure Systems
Please see the folder Product News for further details. (PDF)
The talks were accompanied by posters. A selection of posters available in the publications section of our website
- VITROCELL® ISO 9001 certification – what does change?
Authors: Patricia Hebestreit, Tobias Krebs / VITROCELL® Systems
- New holder for ENDS products for VITROCELL® Smoking Machines and Robots
Authors: Bastian Gutmann, Tobias Krebs / VITROCELL® Systems
- Media insert for VITROCELL® 6 and 12 Exposure Modules
Authors: Oliver Wisser1, Bastian Gutmann1, Adam Seymour2
1VITROCELL® Systems / 2Covance Laboratories Ltd
- VITROCELL® High Throughput Exposure Module: Deposition and Cytotoxicity of Smoke/Aerosol from Different Tobacco Product Types
Authors: Robert Leverette1, Brian Keyser1, Adam Seymour2, Michael Hollings2 and Betsy Bombick1
1RAI Services Company / 2Covance Laboratories Ltd
- Utilization of a human in vitro airway epithelial tissue model to evaluate the respiratory toxicity of orthophthalaldehyde
Author: Diego Rua / FDA/CDRH
- 3D Models for the Alveolar Barrier
Author: Arno Gutleb / LIST
- In vitro model for the prediction of respiratory sensitization
Author: Chary A., Serchi T., Cambier S., Moschini E., Contal S., Hennen J., Ezendam J., Blömeke B., Gutleb A.C./ LIST
- Sub-ohm vaping is cytotoxic, alters gene expression and levels of reactive oxygen-nitrogen species in human lung epithelial cells
Authors: Alexandra Noël, Ekhtear Hossain, Rakeysha Pinkston / Louisiana State University
- Molecular signature of asthma-enhanced sensitivity to aerosols of pristine and carboxylated CuO nanoparticles, identified in 3D cell models
Authors: Ingeborg Kooter, Marit Ilves, Mariska Gröllers-Mulderij, Evert Duistermaat, Peter C. Tromp, Frieke Kuper, Pia Kinaret, Kai Savolainen, Dario Greco, Piia Karisola, Joseph Ndika, Harri Alenius / TNO
- Characterization of an Air-Liquid-Interface (ALI) In Vitro Exposure System (VITROCELL® VC1/7 and VITROCELL® 24/48)
Using a Prototype E-vapor Product Authors: Jingjie Zhang1, Michael Oldham1, Utkarsh Doshi1, I. Gene Gillman2, Russell L. Wolz2, Pavel Kosachevsky2, Bonnie Coffa1, Willie J. McKinney1, K. Monica Lee1
1Altria / 2Enthalpy
- Comparison of Deposition Efficiency and Uniformity of Monodisperse Solid Particle Deposition in Two Air Liquid Interface (VITROCELL® 24/48 and AMES 48) In Vitro Exposure Systems with Computational Fluid Dynamic (CFD) Predictions
Authors: Michael Oldham1, Jingjie Zhang1, I. Gene Gillman2, Pavel Kosachevsky2, F. Lucci3, A. K. Kuczaj3, N. D. Castro1, A. A. Rostami1, Y. B. Pithawalla1, Julia Hoeng3, Willie J. McKinney1, K. Monica Lee1
1Altria / 2Enthalpy / 3PMI
The next VITROCELL® User Group Meeting will be held In Europe on 13 May 2020 in the Europa-Park Rust, Germany. Details will be announced on our website.
Waldkirch, March 10, 2019
