Advanced in vitro exposure systems.

New Products at VITROCELL® User Group Meeting 2019

10. Mar. 2019

09 March 2019, Hilton Inner Harbour Hotel, Baltimore, USA

Following the VITROCELL® User Group Meeting 2018 in San Antonio, Texas, USA, international scientists from Europe, Japan, Korea and USA reconvened in March 2019.

The informal event organized into short presentations and posters was followed by open discussions. It was an excellent opportunity to discuss the latest developments of VITROCELL®, to exchange your experience in working with the equipment and to meet other fellow researchers.
The meeting took place prior to the international Society of Toxicology 58th Annual Meeting and ToxExpo, March 10 – 14, 2018, in Baltimore, USA - one of the largest international conferences related to toxicology.

Focus of the event was to share VITROCELL® activities since the last meeting, to exchange latest research results, to give an update on VITROCELL’s participation in major research programs as well as the presentation of new products for 2019.

Highlights were:

  • Update on validation of the VITROCELL® 24/48 and AMES 48 exposure systems:
    7 doses @ 6 replicates plus one clean air control @ 6 replicates.
    VITROCELL AMES 48
  • Versatile 5-channel linear smoking machine VITROCELL® VC 1 S-TYPE:
    for chemical characterization and in vitro testing of electronic and combustion cigarettes as well as next generation products (NGP).
    VITROCELL VC 1 S-TYPE
  • VITROCELL® Powder Atomizer:
    for aerosolization of dry powders
    VITROCELL QCM
  • Flow Control Software:
    for setting and monitoring of flow controllers for dilution air flow
    VITROCELL QCM
  • New VITROCELL® Cloud Systems
    VITROCELL® Cloud PowerVent and Cloud MAX
    :
    for evacuation of residual gaseous compounds and nebulization of smallest volumes
    VITROCELL Carbon Automated Exposure Stations
  • VITROCELL® Holder System for e-cigarettes:
    Secure and tight connection of any puff-actuated device to Smoking Machine
    Holder System
  • Media Inserts for VITROCELL® Exposure Modules 6 & 12 Series:
    Easier maintenance
    Media Insert
  • Integration of the AlveoliX Lung-on-Chip into VITROCELL® exposure Systems
     AlveioliX

 

Please see the folder Product News for further details. (PDF)

 

The talks were accompanied by posters. A selection of posters available in the publications section of our website

  • VITROCELL® ISO 9001 certification – what does change?
    Authors: Patricia Hebestreit, Tobias Krebs / VITROCELL® Systems
  • New holder for ENDS products for VITROCELL® Smoking Machines and Robots
    Authors: Bastian Gutmann, Tobias Krebs / VITROCELL® Systems
  • Media insert for VITROCELL® 6 and 12 Exposure Modules
    Authors: Oliver Wisser1, Bastian Gutmann1, Adam Seymour2
    1VITROCELL® Systems / 2Covance Laboratories Ltd
  • VITROCELL® High Throughput Exposure Module: Deposition and Cytotoxicity of Smoke/Aerosol from Different Tobacco Product Types
    Authors: Robert Leverette1, Brian Keyser1, Adam Seymour2, Michael Hollings2 and Betsy Bombick1
    1RAI Services Company / 2Covance Laboratories Ltd
  • Utilization of a human in vitro airway epithelial tissue model to evaluate the respiratory toxicity of orthophthalaldehyde
    Author: Diego Rua / FDA/CDRH
  • 3D Models for the Alveolar Barrier
    Author: Arno Gutleb / LIST
  • In vitro model for the prediction of respiratory sensitization
    Author: Chary A., Serchi T., Cambier S., Moschini E., Contal S., Hennen J., Ezendam J., Blömeke B., Gutleb A.C./ LIST
  • Sub-ohm vaping is cytotoxic, alters gene expression and levels of reactive oxygen-nitrogen species in human lung epithelial cells
    Authors: Alexandra Noël, Ekhtear Hossain, Rakeysha Pinkston / Louisiana State University
  • Molecular signature of asthma-enhanced sensitivity to aerosols of pristine and carboxylated CuO nanoparticles, identified in 3D cell models
    Authors: Ingeborg Kooter, Marit Ilves, Mariska Gröllers-Mulderij, Evert Duistermaat, Peter C. Tromp, Frieke Kuper, Pia Kinaret, Kai Savolainen, Dario Greco, Piia Karisola, Joseph Ndika, Harri Alenius / TNO
  • Characterization of an Air-Liquid-Interface (ALI) In Vitro Exposure System (VITROCELL® VC1/7 and VITROCELL® 24/48)
    Using a Prototype E-vapor Product Authors: Jingjie Zhang1, Michael Oldham1, Utkarsh Doshi1, I. Gene Gillman2, Russell L. Wolz2, Pavel Kosachevsky2, Bonnie Coffa1, Willie J. McKinney1, K. Monica Lee1
    1Altria / 2Enthalpy
  • Comparison of Deposition Efficiency and Uniformity of Monodisperse Solid Particle Deposition in Two Air Liquid Interface (VITROCELL® 24/48 and AMES 48) In Vitro Exposure Systems with Computational Fluid Dynamic (CFD) Predictions
    Authors: Michael Oldham1, Jingjie Zhang1, I. Gene Gillman2, Pavel Kosachevsky2, F. Lucci3, A. K. Kuczaj3, N. D. Castro1, A. A. Rostami1, Y. B. Pithawalla1, Julia Hoeng3, Willie J. McKinney1, K. Monica Lee1
    1Altria / 2Enthalpy / 3PMI

The next VITROCELL® User Group Meeting will be held In Europe on 13 May 2020 in the Europa-Park Rust, Germany. Details will be announced on our website.

Waldkirch, March 10, 2019

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