Advanced in vitro exposure systems.

Smoking Machine VC 1 S-TYPE

Smoking Machine VC 1

The manual smoking machine VC 1 S-TYPE is specifically designed and manufactured to fulfill the requirements of chemical characterization and in vitro experiments. Suitable for conventional and electronic cigarettes.

Optimal when researching whole aerosol, it offers significant advantages over other commercial smoking machines.


Components top view
  • Generation of aerosol with the shortest distance to cell cultures or analysing equipment
    For the success of an experiment with whole aerosol it is vital that the distance between the aerosol generation (product holders) and the VITROCELL® cell exposure system or to e.g. impingers is as short as possible to guarantee authentic aerosol-composition.
  • Open and flexible system / incorporation of other analytical tools
    The VC 1 S-TYPE machine is ­designed to allow easy access to all tubing, filters and the pump system. ­Additional analytical ­equipment relevant to the experiment can be easily and individually installed.
  • Freely programmable parameters
    The control system facilitates highly flexible programming of the puffing process. All parameters like puff duration, puff volume, puff frequency and exhaust duration can be defined according to experiment requirements.
  • High flexibility for all smoking regimes
    ISO, Health Canada Intense, Massachusetts, Square and Human Puff Profile regimes (option) can be smoked. An upgrade for Shisha smoking is available.
  • Statistics
    Smoking process data are logged into an Excel® sheet for further processing.
  • Machine dimensions are suitable for constrained lab workplaces
    The VC 1 S-TYPE machine is divided into 4 major components: computer, ­control box with syringe drive platform, impinger and device rack.
  • All components are easy to clean
    In particular the work with unfiltered whole aerosol demands frequent cleaning of all machine parts which come into contact with aerosol. Cleaning must take place after each experiment to avoid any residual product ­contamination to subsequent experiments. Easy access to all component parts ensures quick and efficient cleaning.
  • Human puff profile capability
    This optional feature offers the ­possibility to upload human puff-­profile data registered by ­Smoking Puff Analyzers to the ­machine controls.
  • Compatibility with existing lab systems
    The VC 1 S-TYPE machine can be integrated with and connected to other lab systems, e.g. analytical instruments.
  • Compliance with ISO 3308:2012
    The VC 1 S-TYPE machine meets the ­requirements of ISO 3308:2012 which assures compatibility with data ­generated for quality assurance ­purposes on other smoking machines.
  • Compliance with Health Canada / CRM 81 Conditions
    The VC 1 S-TYPE machine meets the requirements of 55 ml / 30 sec puff frequency for puffing combustion as well as electronic cigarettes.
  • Quality
    The VC 1 S-TYPE machine is built to the highest standards using reliable and durable components. Precision of the process is ensured by a linear motor drive for the piston.
  • Service
    All VC 1 S-TYPE machines are ­designed to be exceptionally ­service-friendly and have a secure internet-based remote servicing module.
  • Software Controls
    Input is communicated via PC with monitor or laptop (part of delivery).

Components Top View

Components top view

Special features of the VITROCELL VC 1 S-TYPE Smoking Machine

  • Max. of 5 ports for e-cigarettes, NGP‘s and conventional cigarettes
  • For chemical analysis and in vitro applications
  • No cross-contamination in product change due to change parts and very easy cleaning
  • Capable of all current regimes ISO, HCI, CRM 81 and up to 300 ml puff volume
  • Small dead volumes
  • Integrated button actuators
Configuration 1

Configuration 1:
chemical analysis „e-cigarettes / NGP‘s“

1 Control Box with Syringe Drive
2 Impinger Rack
3 Filter Holders
4 Examples of e-cigarettes / NGP's with integrated VITROCELL® Vapestarter
5 Integrated Button Actuators
Configuration 2

Configuration 2:
in vitro „e-cigarettes / NGP‘s“

1 Control Box with Syringe Drive
2 Examples of e-cigarettes / NGP's with integrated VITROCELL® Vapestarter
3 In vitro Exposure System
4 Integrated Button Actuators
Configuration 3

Configuration 3:
chemical analysis „Conventional Cigarettes“

1 Control Box with Syringe Drive
2 Impinger Rack
3 Filter Holders
4 Smoking Box
5 Sidestream Exhaust Tubes
Configuration 4

Configuration 4:
in vitro „Conventional Cigarettes“

1 Control Box with Syringe Drive
2 Smoking Box
3 Sidestream Exhaust Tubes
4 In vitro Exposure System

Technical Data

Dimensions without racks
605 x 455 x 533 mm (L x W x H)

1 x 208-240 V, 50/60 Hz, 4 A

Compressed air
4 bar (58 psi) min.

Remote service module
Included / Internet access mandatory

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