Advanced in vitro exposure systems.

For the exposure to liquid aerosols


This system is specifically designed for dose-controlled and spatially uniform deposition of liquid aerosols on cells cultured at the air/liquid interface. The aerosol is applied for a short time of approx. 3-4 minutes.

VITROCELL® Cloud System Phase 1
Phase 1 - Emission of Cloud
VITROCELL® Cloud System Phase 2
Phase 2 - Homogeneous Mixing
VITROCELL® Cloud System Phase 3
Phase 3 - Gravitational Settling

The base module is made of electropolished stainless steel. It has an electronically controlled heating unit. The Cloud aerosol chamber is made of polycarbonate.

VITROCELL® offers 2 options for aerosol generation:

  • Aeroneb® Lab with a particle size of 4.0 μm - 6.0 μm VMD or
  • Aeroneb® Pro with a larger span of 2.5 to 6.0 μm VMD

Nebulizers for larger particle sizes are available upon request.

The VITROCELL® Cloud can be used for aerosols generated from liquids and suspensions. Possible fields of application include screening for inhaled drugs and toxicity testing of inhaled substances including nanoparticle suspensions.


  • New exposure system for liquid aerosols
  • High droplet output rate – cloud dynamics
  • No external air-flow required (simple)
  • No humidity control required
  • Dose-controlled and spatially uniform aerosol deposition
  • Small residual volume in nebulizer reservoir
  • Easy handling
  • Clinically relevant
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