Advanced in vitro exposure systems.

VITROCELL® 6/48 for 6-well sized inserts

VITROCELL® 6/48 for 6-well sized inserts

The VITROCELL® 6/48 module system has been specifically designed and engineered to facilitate the research of mammalian cell cultures in direct exposure to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of human physiological exposure.

Only one system is required: 7 dilutions with 6 inserts are used for exposure to the substances and 6 inserts in the same system for clean air control. The cells are exposed at the air / liquid interface on 48 cell culture inserts using low flow rates of the aerosol. A complete dose / response profile can be obtained in one experiment. After exposure, the cells are further processed to measure a wide range of endpoints, e. g. cytotoxicity, ­genotoxicity, proliferation, cellular ­and oxidative stress as well as inflammation (see also VITROCELL® assay guide).

Features

  • Suitable for COSTAR®, FALCON® and ThinCert® 6-well sized cell culture inserts
  • Base module compartments made of titanium for maximum durability
  • Hyperboloid geometry of inlets for optimized particle deposition and distribution
  • Available inlet materials: Teflon, stainless steel, stainless steel with unique VITROGLIDE surface treatment
  • Heating base plate with electronic control
  • An additional incubator is not required while using this module
  • Autoclavable at 121° C (250° F)
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