for VITROCELL® Customers
 May 20, 2014
 Europa-Park Rust, Germany
 >> direct link for download
See us at:

 nanoTox 2014, 
 Antalya, Turkey

 European Society of
 Toxicology In Vitro 2014
 June 10-13, 2014
 Egmond aan Zee
 The Netherlands

 9th World Congress on
 Alterna­tives and Animal Use
 August 24–28, 2014
 Prague, Czech Republic

 September 7 - 10, 2014 
 Edinburgh, Scotland, UK

 March 2014
 NEW on SOT Phoenix
 VITROCELL® Catalogue 04/13
 >> VITROCELL® Livebook
 >> Catalogue download
 VITROCELL® 6/6 Module
 >> direct link

 July 2013
 NEW on
 ICT Seoul
 Exposure System for
 Aerosols with Cloud Dynamics
 >> direct link Cloud Leaflet
 VITROCELL® Aerosolist
 Automated Sampling S
 Aerosol Monitoring
 >> direct link Aerosolist

 April 2013: VITROCELL® 
 User Group Meeting
  >> News release
 March 2013:
 NEW on SOT San Antonio
 VITROCELL® Catalogue 03/13
VITROCELL® 12/4 Module
direct link
 VITROCELL® 24/48 System
 - for 8 doses @ 6 replicates
 - liquid aerosol option
direct link
 VITROCELL® Skin Autosampler
 validated >>
direct link 
 New Dosimetry Software
direct link
 February 2013: 
 New Video VITROCELL® 
 Skin Autosampler >> direct link

 News Archive >> direct link









 Scope of Activities: Systems for Inhalation Toxicology and Percutaneous Penetration

 In Vitro Cultivation and Exposure Systems for Inhalation Toxicology

We offer customers from industry and research institutes new culture and exposure systems for in vitro studies of gases or complex mixtures. The VITROCELL® modules offer new possibilities for the characterization of the effects of airborne substances such as:


> Gases 
> Complex mixtures
> Nano particles
> Fibres

Application Areas
- Combustion exhaust
- Cosmetics
- Household chemicals 
- Indoor / outdoor air analysis
- Industrial chemicals
- Pesticides
- Pharmaceuticals
- Tobacco smoke (whole smoke and gas phase)

Direct Exposure Technology 
at the Air / Liquid Interface

Primary cultures and cell lines, e.g. from the respiratory tract, are treated in modules specially designed for direct contact between cells and components of the test atmosphere at the air/liquid interface. 

The advantages:

- No loss
- No solution / no dissolution
- No reaction of constituents with medium

The result: High sensitivity of the system

    Flow principle download (3.3 MB wmv)
 Please visit the System elements section for a typical system flow chart  >> direct link

 VITROCELL®  Cultivation and Exposure Modules

 For cultivation and direct exposure of cells or bacteria. We offer a wide range 
modules engineered for normal to high throughput.
direct link

 Complete Exposure Systems including Aerosol Generators
 Turn-key systems including aerosol generators for substances in liquid or powder
 form as well as various solutions for dose monitoring.
direct link

 VC 10® Smoking Machines

 VITROCELL® Smoking Machines are designed to the specific needs in in vitro,
 chemical and medical research.
direct link


 VITROCELL® Equipment for Dose Monitoring

 VITROCELL® Photometers are designed to perform online measurements of 
 the particle mass at very low flow rates without particle losses.

  >> direct link

 VITROCELL® Quartz Crystal Microbalance (QCM) sensors enable to measure the
 particle deposition online in ng/cm2 at a resolution of 10 ng/cm2.
  >> direct link

 In Vitro Exposure Sytems for Tissue / Percutaneous Penetration
 VITROCELL® Skin Exposure Systems
 The VITROCELL® Skin modules are unique alternatives to Franz Cells. 
 They are suitable for the exposure of tissue to liquids and other compounds 
 as well as for the analysis of volatiles. 
 The modules are available in various sizes and configurations. It is in combination
 with the VITROCELL® Skin Autosampler a powerful analysis tool.
direct link


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