| Scope of Activities: Systems for Inhalation Toxicology and Percutaneous Penetration |
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| In Vitro Cultivation and Exposure Systems for Inhalation Toxicology |
| We offer customers from industry and research institutes new culture and exposure systems for in vitro studies of gases or complex mixtures. The VITROCELL® modules offer new possibilities for the characterization of the effects of airborne substances such as: |
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> Gases
> Complex mixtures
> Nano particles
> Fibres
Application Areas
- Combustion exhaust
- Cosmetics
- Household chemicals
- Indoor / outdoor air analysis
- Industrial chemicals
- Pesticides
- Pharmaceuticals
- Tobacco smoke (whole smoke and gas phase)
Direct Exposure Technology
at the Air / Liquid Interface
Primary cultures and cell lines, e.g. from the respiratory tract, are treated in modules specially designed for direct contact between cells and components of the test atmosphere at the air/liquid interface.
The advantages:
- No loss
- No solution / no dissolution
- No reaction of constituents with medium
The result: High sensitivity of the system
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Flow principle download (3.3 MB wmv) |
| Please visit the System elements section for a typical system flow chart >> direct link |
| VITROCELL® Cultivation and Exposure Modules |
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For cultivation and direct exposure of cells or bacteria. There is a wide range
of modules engineered for normal to high througput.
>> direct link
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| Complete Exposure Systems including Aerosol Generators |
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Turn-key systems including aerosol generators for substances in liquid or powder
form as well as various solutions for dose control.
>> direct link |
| VC 10® Smoking Machines |
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VITROCELL® Smoking Machines are designed to the specific needs in in vitro,
chemical and medical research.
>> direct link
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| VITROCELL® Equipment for Dose Control |
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VITROCELL® Photometers are designed to perform online measurements of
the particle mass at very low flow rates without particle losses.
VITROCELL® Quartz Crystal Microbalance (QCM) sensors enable to measure the
particle deposition online in nanogram/cm2.
>> direct link
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| In Vitro Exposure Sytems for Tissue / Percutaneous Penetration |
| VITROCELL® Skin Exposure Systems |
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The VITROCELL® Skin modules are unique alternatives to Franz Cells.
They are suitable for the exposure of tissue to liquids and other compounds
as well as for the analysis of volatiles.
The modules are available in various sizes and configurations. It is in combination
with the VITROCELL® Skin Autosampler a powerful analysis tool.
>> direct link |
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