Advanced in vitro exposure systems.

VITROCELL® High Throughput Exposure Module: Deposition and Cytotoxicity of Smoke/Aerosol from Different Tobacco Product Types

25. Oct. 2019

User Group Meeting 2019

1Leverette R, 1Keyser B, 2Seymour A, 2Hollings M and 1Bombick B
1Scientific & Regulatory Affairs, RAI Services Company Winston-Salem, NC 27102
2Covance Laboratories Ltd Otley Road, Harrogate, North Yorkshire HG3 1PY, UK

Abstract
The continued development of whole smoke/aerosol exposure systems provides a means to conduct in vitro assessment of freshly generated whole smoke and aerosol from either combustible or tobacco heating products (THP) and electronic nicotine delivery systems (ENDS), respectively. A challenge with such exposure systems is ensuring sufficient sample throughput for in vitro toxicological studies in a timely manner.

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