Autor
David Thorne, British American Tobacco
Workshop series to identify, discuss and develop recommendations for the optimal generation and use of in vitro data for product regulation.
Conclusions
• In vitro techniques have to evolve alongside new emerging products
• Can not rely on traditional cigarette smoke testing approaches. These new categories are chemically and physically different and should be treated as such
• Future e-cigarette (&THP) testing should consider the following aspects to ensure appropriate conclusions/interpretation of data:• Aerosol delivery (Dose) • Applied dosimetry approaches to make the data more meaningful (bridging of data) • Contextualisation of data through human consumption and dose extrapolation
• We have demonstrated the evolution of techniques, which has allowed us to bridge between platforms, simplify exposure setup, experimental design and demonstrate e-cigarette technology evolution
