Advanced in vitro exposure systems.

Exposure of human lung cells to native diesel motor exhaust-development of an optimized in vitro test strategy

30. Apr. 2002

Toxicology in Vitro

Volume 16, Issue 2, pp. 185-192, April, 2002

Authors
J.W. Knebel, D. Ritter, M. Aufderheide

 

The experimental set-up allows the investigation of native diesel exhaust using short distances for the transportation of the gas to the target cells. Cell viability was not influenced by the exposure to clean air, whereas dose-dependent cytotoxicity was found contingent on the dosage of exhaust.

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