Advanced in vitro exposure systems.

for the exposure of skin tissue to liquid aerosols

This system is specifically designed for dose-controlled and spatially uniform deposition of liquid aerosols on skin samples. The aerosol is applied for a short time of approx. 3-4 minutes.

VITROCELL® Cloud System Phase 1
Phase 1 - Emission of Cloud
VITROCELL® Cloud System Phase 2
Phase 2 - Homogeneous Mixing
VITROCELL® Cloud System Phase 3
Phase 3 - Gravitational Settling

The base module is made of electropolished stainless steel. It has an electronically controlled heating unit. The Cloud aerosol chamber is made of polycarbonate.

VITROCELL® offers 2 options for aerosol generation:

  • Aeroneb® Lab with a particle size of 4.0 μm - 6.0 μm VMD or
  • Aeroneb® Pro with a larger span of 2.5 to 6.0 μm VMD

Nebulizers for larger particle sizes are available upon request.

The VITROCELL® Cloud can be used for aerosols generated from liquids and suspensions. Possible fields of application include toxicity testing including nanoparticle suspensions.

The unique tissue holders have been specifically designed to enable tight and reliable skin fixation. This module is a legitimate and superior alternative to Franz cells.



  • Exposure system for liquid aerosols
  • High droplet output rate - cloud dynamics
  • No external air-flow required (simple)
  • No humidity control required
  • Dose-controlled and spatially uniform aerosol deposition
  • Small residual volume in nebulizer reservoir
  • Easy handling
  • Unique tissue holder
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