Advanced in vitro exposure systems.

New lung model gives lab animals a breather

26. Mar. 2020

A first-of-its-kind 3D lung model could replace animals in inhalation toxicity research.

Autor

Francesca Lake

Source
Barosova H, Maione AG, Septiadi D et al. Use of EpiAlveolar lung model to predict fibrotic potential of multiwalled carbon nanotubes. ACS Nano

doi:10.1021/acsnano.9b06860 (2020);
https://pubs.acs.org/doi/10.1021/acsnano.9b06860
https://www.eurekalert.org/pub_releases/2020-03/pfte-psg032420.php

 

The model utilizes an air–liquid interface exposure device, VITROCELL Cloud, which PETA had awarded to the Heriot–Watt group in 2017 along with three other groups, in an attempt to support the development of non-animal toxicity testing methods.

 

PETA International Science Consortium Ltd (London, UK) – the People for the Ethical Treatment of Animals – has provided funding to support MatTek Life Sciences (MA, USA) in their development of the first nonanimal 3D lung alveolar model of its kind. Called EpiAlveolar™, the model can be used to study the effects of chemical, material or pathogen inhalation on the lung, without the need for animal involvement.

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Categories: Publications

Tags: VITROCELL Cloud

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