VITROCELL Systems

The VITROCELL® Automated Exposure Station has been specifically designed and engineered to facilitate the research of mammalian cell cultures in direct exposure to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of human physiological exposure. It offers a capacity of up to 18 cell culture compartments for exposure and 6 compartments for clean air control. All key functions for successful exposure such as, aerosol flow rates, humidity, temperature and leak test are edited by touch-screen prior to the experiment . The respective data is shown on live graphs and stored for further analysis. The cells are exposed at the air/liquid interface on 6/12/24well sized cell culture inserts. The isokinetic sampling system enables a uniform and reproducible delivery of the test substance to the cells. Applying an electrical field increases deposition efficiency. Post-exposure the cells are further processed to measure a wide range of endpoints, e.g. cytotoxicity, genotoxicity, proliferation, cellular and oxidative stress as well as inflammation. See also the VITROCELL® assay guide for further information. VITROCELL® Automated Exposure Station User friendly solution with high tech features • for 6, 12 and 24-well sized cell culture inserts as well as Petri dishes Automated Test System Optional VITROCELL® 6/6 CF modules 78

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