VITROCELL Systems

VITROCELL® 6/6 Exposure Module For 6 cell culture inserts (6-well size) The VITROCELL® 6/6 module system has been specifically designed and engineered to facilitate the research of mammalian cell cultures in direct exposure to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of human physiological exposure. Normally only one system is required: 1 dilution with 3 inserts is used for for exposure to the substances and 3 inserts in the same system for clean air control. The cells are exposed at the air/ liquid interface on 6 cell culture inserts using low flow rates of the aerosol. After exposure, the cells are further processed to measure a wide range of endpoints, e. g. cytotoxicity, genotoxicity, proliferation, cellular and oxidative stress as well as inflammation (see also VITROCELL® assay guide). 1 dose @ 3 replicates 1 control @ 3 replicates Compact Design Culture media supply The media is supplied to the module by gravimetric method, syringe or using a media pump for intermittent / continuous media exchange. 20

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