David Thorne, Sophie Larard, Andrew Baxter, Clive Meredith, Marianna Gaҫa
British American Tobacco, R&D Centre, Southampton, Hampshire, SO15 8TL, UK
H I G H L I G H T S
Cigarette smoke generates a dose dependent increase in double strand breaks.
E-cigarette aerosols did not generate any increases in double strand breaks above control levels.
E-cigarette exposures were approximately 28-fold greater than that of cigarette smoke exposures.
In vitro dosimetry ensures accurate interpretation of the data, and confirms delivery of test agent.
In vitro dosimetry allows cross-product, study and system comparisons.