Advanced in vitro exposure systems.

2. Nov. 2020

Influence of the environmental relative humidity on the inflammatory response of skin model after exposure to various environmental pollutants

https://doi.org/10.1016/j.envres.2020.110350

Emeline Seurat a, Anthony Verdin b, Fabrice Cazier c, Dominique Courcot b, Richard Fitoussi d, Katell Vi´e d, Val´erie Desauziers e, Isabelle Momas a, Nathalie Seta a, Sophie Achard a
a Laboratoire de Sant´e Publique et Environnement, Hera “Health Environmental Risk Assessment”, Inserm UMR1153-CRESS (Centre de Recherche en Epid´emiologie et StatistiqueS), Universit´e de Paris, Facult´e de Pharmacie de Paris, 4, Avenue de L’Observatoire, 75006, Paris, France
b Unit´e de Chimie Environnementale et Interactions sur le Vivant UR4492, SFR Condorcet FR CNRS 3417, Maison de La Recherche en Environnement Industriel 2, Universit´e Du Littoral Cˆote D’Opale, 189A Avenue Maurice Schumann, 59140, Dunkerque, France
c Centre Commun de Mesures (CCM), Universit´e Du Littoral-Cˆote D’Opale, 145 Avenue Maurice Schumann, 5914, Dunkerque, France
d Laboratoires Clarins, 5 Rue Amp`ere, 95300, Pontoise, France
e IPREM, IMT Mines Ales, Universit´e de Pau et des Pays de L’Adour, E2S UPPA, CNRS, Pau, France

 

In the course of this study, they tested various pollutants with different chemical compositions, applying them to the apical side of Reconstructed Human Epidermis and being particularly interested in the effect relative humidity has on the reaction to pollutants. Investigating several cytokines and chemokines, they showed that IL-1α, IL-6, IL-8, and RANTES are the cytokines/chemokines almost systematically induced by most pollutants.

 

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18. Sep. 2020

VITROCELL® Shisha Testing System for Cell Cultures

For in vitro testing of water pipe tobacco at the air / liquid interface

New designs of electronic cigarettes such as ENDS (Electronic Nicotine Delivery Systems) products or HTP (Heated Tobacco Products) lead to a large variety of different shapes which make the insertion into conventional holders with labyrinth seals impossible. VITROCELL® has developed a new holder system which is flexible to adjust to different shapes.

VITROCELL Application Note

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27. Jul. 2020

Vitrocell® holder systems for e-cigarettes

Secure and tight connection of any device to the smoking machine.

New designs of electronic cigarettes such as ENDS (Electronic Nicotine Delivery Systems) products or HTP (Heated Tobacco Products) lead to a large variety of different shapes which make the insertion into conventional holders with labyrinth seals impossible. VITROCELL® has developed a new holder system which is flexible to adjust to different shapes.

VITROCELL Application Note

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25. Jun. 2020

Novel TEM Grid holders for dose determination of airborne particles during in vitro Exposure at the air / liquid interface

The assessment of toxicological effects of airborne particles to the human organism is of major importance in disease research. The presence of nano and ultrafine particles can be found both in indoor and outdoor atmospheres which include workplaces and living areas. Over the last years, the degree of contribution to diseases of such particles is analyzed ever more frequent by the use of in vitro methods. The required equipment for these studies consisting of aerosol generation and exposure systems are nowadays developed more and more to proven levels.

VITROCELL Application Note.

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31. Mar. 2013

New on SOT San Antonio

VITROCELL® Skin Autosampler validated

After successful introduction of the VITROCELL autosampler in 2012 our lead customer Beiersdorf AG has validated the system. It is a powerful tool for kinetics in skin penetration.

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Categories: Product News

Tags: skin, autosampler

14. Mar. 2013

Comparison of a new skin penetration system containing a toxicokinetic module with Franz diffusion cells

SOT San Antonio, Texas, USA

March 10-14, 2013

Authors
D. Gerstel, I. Herberz, M. Akhiani, S. Mueller , H. Wenck, A. Schepky

Beiersdorf AG, Toxicology, Hamburg, Germany

 

This poster shows the successfull development of a semiautomated skin-penetration-system on a Vitrocell® skin exposure module in conjunction with FRANZ diffusion cells.

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Categories: Publications

Tags: skin, autosampler

28. Feb. 2013

New Video

VITROCELL® Skin Autosampler

View the this powerful tool for kinetics in percutaneous penetration in action.

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Categories: Product News

Tags: skin, autosampler

6. Sep. 2012

New in Linz

VITROCELL® Skin Autosampler for automated sampling of receptor fluid

A new step for automation in skin penetration research.

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Categories: Product News

Tags: skin, autosampler

20. Jun. 2012

Comparison of a new skin penetration system containing a toxicokinetic modul with Franz diffusion cells

EUROTOX 2012

June 17-20, 2012. Stockholm, Sweden.

Authors
D. Gerstel1, N. Metke2, S. Mueller1, I. Herberz1, M. Akhiani1, CD Wacker2, H. Wenck1, A. Schepky1

1 Beiersdorf AG, Hamburg, Germany
2 Hochschule für angewandte Wissenschaften Hamburg, Hamburg, Germany

 

Testing a semiautomated skin penetration system based on a penetration cell from VITROCELL® Systems to its comparability to Franz diffusion cells.

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Categories: Publications

Tags: skin

31. Mar. 2011

VITROCELL® Skin Exposure System for Tissue

New module to replace Franz diffusion cells in skin testing

Comments (0) Number of views (1364)

Categories: Product News

Tags: skin

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