2010 Jun 1;245(2):219-25. doi: 10.1016/j.taap.2010.03.003. [Epub ahead of print]
Koehler C., Ginzkey C., Friehs G., Hackenberg S., Froelich K., Scherzed A., Burghartz M., Kessler M., Kleinsasser N.
Department of Oto-Rhino-Laryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, University of Wuerzburg, Germany
Nasal epithelial cells of were cultured in an air-liquid interface and exposed to NO(2). After exposure, genotoxicity was evaluated by the Comet assay and the micronucleus test. Depression of proliferation and cytotoxic effects were determined using the micronucleus assay and trypan blue exclusion assay.