Advanced in vitro exposure systems.

3. Sep. 2013

Characterisation of a Vitrocell® VC 10 in vitro smoke exposure system using dose tools and biological analysis

Chemistry Central Journal 2013, 7:146

doi:10.1186/1752-153X-7-146

Authors
David Thorne1, Joanne Kilford2, Rebecca Payne2, Jason Adamson1, Ken Scott1, Annette Dalrymple1, Clive Meredith1 and Deborah Dillon1

1 British American Tobacco, Group R&D, Southampton, United Kingdom
2 Covance Laboratories Ltd, Harrogate, North Yorkshire, United Kingdom

 

The study demonstrated that the VC 10® can produce stable tobacco smoke dilutions by particulate deposition, measured vapour phase, smoke marker delivery and biological responses from two independent in vitro test systems. 

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30. Jul. 2013

New on ICT Seoul

VITROCELL® Aerosolist

Automated Sampling System for Aerosol Monitoring.

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Categories: Product News

Tags: aerosolist

30. Jul. 2013

New on ICT Seoul

VITROCELL® Cloud

Exposure System for Liquid Aerosols with Cloud Dynamics.

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29. Jul. 2013

Evaluation method for the cytotoxicity of cigarette smoke byin vitro whole smoke exposure

https://doi.org/10.1016/j.etp.2013.07.004

Xiang Li, Cong Nie, Pingping Shang, Fuwei Xie, Huimin Liu, Jianping Xie

Key Laboratory of Tobacco Chemistry, Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, China

With the development of direct exposure technology at the air/liquid interface, the toxicological responses of fresh WS can be evaluated. The whole smoke of the 3R4F reference cigarette and two experimental cigarettes were tested on Chinese hamster ovary (CHO) cells to evaluate the endpoints Ames Salmonella reversemutagenicity assay and in vitro micronucleus assay for genotoxicity and neutral red uptake (NRU)assay for cytotoxicity.

 

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26. Jul. 2013

An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

Particle and Fibre Toxicology 2013, 10:31

doi:10.1186/1743-8977-10-31

Authors
Sebastian G Klein12, Tommaso Serchi1, Lucien Hoffmann1, Brunhilde Blömeke2 and Arno C Gutleb1*

1 Department Environment and Agro-biotechnologies (EVA), Centre de Recherche Public - Gabriel Lippmann, 41 rue du Brill, L-4422 Belvaux, Luxembourg
2 Department of Environmental Toxicology, University of Trier, Universitätsring 15, Trier, Germany

 

Exposition of fine and ultra-fine particles on a tetraculture of A549, TPA-1, HCM-1 and EA.hy 926 cells to measure oxidative stress with the IL-8 and DCFH-DA assay.

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15. Apr. 2013

VITROCELL User Group Meeting

Ascot, United Kingdom

A total of 29 scientists from China, Europe, India, Japan and USA followed the invitation of VITROCELL® Systems to the 2013 User Group Meeting.

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31. Mar. 2013

New on SOT San Antonio

New Dosimetry Software

The new upgrade is the perfect tool for online dose monitoring using VITROCELL photometers and/or crystal quartz microbalances.

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Categories: Product News

Tags: microbalance, photometer

31. Mar. 2013

New on SOT San Antonio

VITROCELL® Skin Autosampler validated

After successful introduction of the VITROCELL autosampler in 2012 our lead customer Beiersdorf AG has validated the system. It is a powerful tool for kinetics in skin penetration.

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Categories: Product News

Tags: skin, autosampler

31. Mar. 2013

New on SOT San Antonio

VITROCELL® 24/48 Module

The new exposure system is a benchmark for in vitro research with higher throughput. It offers up to 8 doses @ 6 replicates in the 24-well size.

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31. Mar. 2013

New on SOT San Antonio

VITROCELL® 12/4 Module

The new exposure module for inserts in the 12-well and 24-well size offers space to integrate a quartz crystal microbalance.

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Comments (0) Number of views (1351)
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