Chary A.1,2, Serchi T.1, Cambier S.1, Moschini E.1, Contal S.1, Hennen J.2, Ezendam J.3, Blömeke B.2, Gutleb A.C.1
1 Department of Environmental Research and Innovation, Luxembourg Institute of Science and Technology (LIST), Luxembourg.
2 Department of Environmental Toxicology, Trier University, Germany. 3Centre for Environmental Protection,National Institute for Public Health and the Environment (RIVM), The Netherlands.
- Adapt a 3D-coculture system previously developed by us (Klein et al. 2013) allowing the study of respiratory sensitization processes by including dendritic cells, which have a crucial role in sensitization
- Find markers for the assessment of the respiratory sensitizing potential of inhaled compounds by measuring the activation of DCs as well as the release of cytokines