Advanced in vitro exposure systems.

11. Mar. 2018

A setup to test toxicity of alcohol inhalation from consumer products

User Group Meeting 2018

Dr. Monique Manche1, Dr. Fabrice Nesslany2, Tobias Krebs3
1Laboratoires Anios, 59260 Lille-Hellemmes, France
2Laboratoire de toxicologie génétique, Institut Pasteur de Lille, 59000 Lille, France
3VITROCELL Systems GmbH, 79183 Waldkirch, Germany

 

Genotoxicity tests (in vitro micronucleus test and comet assay) have been conducted on p53 competent pulmonary cells, with alcohol administration as vapours to obtain data under conditions more representative of actual exposure conditions via the pulmonary route.

 

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11. Mar. 2018

Update on FTIR integration

User Group Meeting 2018

Dr. Martin Kieninger1, Tobias Krebs2

1ANSYCO GmbH, Gasmet Group, 76131 Karlsruhe, Germany

2VITROCELL Systems GmbH, 79183 Waldkirch, Germany

 

The poster shows a reliable, easy to use online analysis tool with fast response and a wide range of components due to Calcmet library. Ideal for quality control and dose monitoring.


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11. Mar. 2018

Photometer Calibration Method

User Group Meeting 2018

Johannes Sood

VITROCELL Systems GmbH, 79183 Waldkirch, Germany

The poster shows a reliable method for the photometer calibration.

 

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Comments (0) Number of views (533)

11. Mar. 2018

VITROCELL® Cloud MAX

User Group Meeting 2018

Patrick Weindl1, Dr. Otmar Schmid2,

1VITROCELL Systems GmbH, 79183 Waldkirch, Germany
2Helmholtz Center Munich, Germany

The poster shows the design for smallest nebulization volumes and high deposition efficiency.

 

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Comments (0) Number of views (250)

11. Mar. 2018

Update: Deposition Enhancement via Thermophoresis

User Group Meeting 2018

Dr. Dirk Brossell

Federal Institute for Occupational Safety and Health (BAuA), Unit 4.5, 10317 Berlin, Germany

The poster demonstrates the particle deposition via thermal precipitation (particle precipitation by thermophoresis) on cells hosted at the air-liquid interface (ALI).
Advantages of thermophoresis
• Diffusion-like mechanism, gentle particle deposition 
• Independent from particle size (for nanoparticles)
• Homogenous deposition density profile 
• No need to manipulate aerosol properties for deposition (charge, size)

 

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11. Mar. 2018

Characterization of a Vitrocell VC1 Using Nicotine Dosimetry: An Essential Component Towards Standardised In Vitro Aerosol Exposure of Tobacco and Next Generation Nicotine Delivery Products

IIVS at SOT 2018

D. Sheehan1, M. Aragon1, J. Adamson2, M. Gaca2, H. Raabe1, and H. Behrsing1.
1Institute for In Vitro Sciences, Inc., Gaithersburg, MD; and 2British American Tobacco, Southampton, United Kingdom.

This study demonstrates successful Vitrocell VC1 aerosol generation and delivery across multiple nicotine product categories (3R4F cigarette smoke, e-liquid and THP), as characterised using nicotine as a dosimetry marker. The data suggests the VC1 can reproducibly generate and deliver tobacco product and NGP aerosols for future in vitro assessment and matches the performance of reported exposure systems.

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Comments (0) Number of views (480)

11. Mar. 2018

VITROCELL® 6/48: Changeover set for 24-well sized inserts

User Group Meeting 2018

Tobias Krebs

VITROCELL Systems GmbH, 79183 Waldkirch, Germany 

 

The poster shows the VITROCEL® 48 exposure system with a 6- and a 24-well setup.

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Comments (0) Number of views (160)

11. Mar. 2018

New design of Monitor Software

User Group Meeting 2018

Johannes Sood
VITROCELL Systems GmbH, 79183 Waldkirch, Germany

The poster demonstrates the new VITROCELL® Monitor software interface.

 

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Categories: Publications

Tags: microbalance, photometer

11. Mar. 2018

VITROCELL® Powder Chamber

User Group Meeting 2018

Katharina Knoth1, Marius Hittinger1, Tobias Krebs2

1PharmBioTec GmbH, Science Park 1, 66123 Saarbrücken, Germany  

2VITROCELL Systems GmbH, 79183 Waldkirch, Germany

The poster shows two customer examples for exposures to smallest quantities of dry powders.

 

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Comments (0) Number of views (195)

11. Mar. 2018

VITROCELL® Cloud SEQ

User Group Meeting 2018

Patrick Weindl, Oliver Wisser

VITROCELL Systems GmbH, 79183 Waldkirch, Germany

The VITROCELL® Cloud SEQ represents another evolution of the well-known Cloud systems. Keeping functional process parameters according to established devices like the VITROCELL® Cloud 6, 12 or 24 it is meant to enhance those devices even further. lt offers the possibility to sequentially expose rows of inserts to create dose-response curves while keeping the concentration of nebulized liquid at the same level and the cell-cultures under highly comparable conditions.


 

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Comments (0) Number of views (181)
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