Highest requirements?Customized solutions! Gases, complex mixtures, nano materials and environmental atmospheres are tested in vitro using our tailor-made exposure systems at the air/liquid interface.
New regulations?Excellent results! Skin tissue is exposed to liquids, powders, pastes and airborne materials in our unique in vitro testing devices with high reproducibility.
Durable components?Long-lasting advantages! Best-in-class components to optimally facilitate vacuum flows, temperature management and humidification of test atmospheres. Perfectly synchronized for VITROCELL® exposure modules.
Working together?Partnership for success! Valuable documentation on all VITROCELL® products, references as well as a compilation of relevant publications make this section a powerful information source for in vitro research.
VITROCELL® Cloud SEQ 24For sequential and multiple exposures to liquid aerosols This system is specifically designed for dose-controlled and spatially uniform deposition of liquid aerosols on cells cultured at the air/liquid interface. The aerosol is applied for a short time of approx. 3 – 4 minutes. Phase 1 - Emission of Cloud Phase 2 - Homogeneous Mixing Phase 3 - Gravitational Settling The VITROCELL® Cloud can be used for aerosols generated from liquids and suspensions. Possible fields of application are screening for inhaled drugs and toxicity testing of inhaled substances including nanoparticle suspensions. There is a choice among 4 options of Aeroneb® nebulizers: 4.0 – 6.0 µm 2.5 – 6.0 µm 2.5 – 4.0 µm 10 µm (special version) The Cloud aerosol chamber is made of Polycarbonate. The VITROCELL® Cloud SEQ represents another evolution of the well-known Cloud system. Keeping functional process parameters according to established devices like the VITROCELL® Cloud 6, 12 or 24 it enhances these devices even further. It offers the possibility to sequentially expose rows of inserts to create dose-response effects via multiple exposures in one experiment. The concentration of nebulized liquid is kept at the same level for each nebulisation and the cell cultures under comparable conditions. VITROCELL® Cloud SEQ 24 without insert cover VITROCELL® Cloud SEQ 24 with two insert covers VITROCELL® Cloud SEQ 24 with four insert covers
Download Leaflet VITROCELL® Cloud SEQ 24 (PDF) Videos VITROCELL® Cloud Exposure System for Liquid Aerosols