Advanced in vitro exposure systems.

For the exposure to liquid aerosols


This system is specifically designed for dose-controlled and spatially uniform deposition of liquid aerosols on cells cultured at the air/liquid interface. The aerosol is applied for a short time of approx. 3-4 minutes.

VITROCELL® Cloud System Phase 1
Phase 1 - Emission of Cloud
VITROCELL® Cloud System Phase 2
Phase 2 - Homogeneous Mixing
VITROCELL® Cloud System Phase 3
Phase 3 - Gravitational Settling

The base module is made of electropolished stainless steel. It has an electronically controlled heating unit. The Cloud aerosol chamber is made of polycarbonate.

VITROCELL® offers 2 options for aerosol generation:

  • Aeroneb® Lab with a particle size of 4.0 μm - 6.0 μm VMD or
  • Aeroneb® Pro with a larger span of 2.5 to 6.0 μm VMD

Nebulizers for larger particle sizes are available upon request.

The VITROCELL® Cloud can be used for aerosols generated from liquids and suspensions. Possible fields of application include screening for inhaled drugs and toxicity testing of inhaled substances including nanoparticle suspensions.

Adaptors for 12- and 24-well sized inserts included

6-well inserts
6-well inserts
12-well inserts
12-well inserts
24-well inserts
24-well inserts


  • New exposure system for liquid aerosols
  • High droplet output rate – cloud dynamics
  • No external air-flow required (simple)
  • No humidity control required
  • Dose-controlled and spatially uniform aerosol deposition
  • Small residual volume in nebulizer reservoir
  • Easy handling
  • Clinically relevant
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