VITROCELL® 6/3, 6/4 and 6/6 CF

Stainless Steel modules for 6-well sized inserts

The VITROCELL® 6 CF module system has been specifically designed and engineered to facilitate research of the direct exposure of human cell cultures to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of anatomical exposure.

Adaptors for 12 and 24-well sized inserts make this exposure system an optimal, universal testing platform.

Base module

The base module is made of electropolished stainless steel for maximum durability and is fully autoclavable for 20 min. at 120° C and higher temperatures.

A constant temperature within the unit (37° C / 99° F) is assured via water circuit heating. Therefore, an additional incubator is not required during exposure. The media are supplied individually to each well compartment. Optionally, media exchange can be carried out on a continuous basis using a precision media pump.

VITROCELL® 6/3 CF base module for 3 inserts
VITROCELL® 6/4 CF base module for 4 inserts
VITROCELL® 6/6 CF base module for 6 inserts
The module has been designed for 3, 4 or 6-cell culture inserts (6-well size).

More about 6/3, 6/4 and 6/6 CF Stainless Steel

Aerosol exposure top

Special sealing and connection mechanisms guarantee a hermetic connection of the base module with the aerosol exposure top.

The aerosol inlet-stream flows through specially shaped inlets. The stainless steel / VITROGLIDE inlets are specifically designed for aerosols containing nanoparticles. The aerosol exposure top features an in/outlet for heating the water circuit, ensuring corresponding temperatures with the base module. It is made of high-quality anodized aluminum.

Microbalance Sensor – Additional option

A choice of modules equipped with 1 Quartz Crystal Microbalance for dose monitoring is also available.


Universal module with optional adaptor sets for:

  • 12-well sized inserts
  • Snapwell® inserts
  • 24-well sized inserts
  • 35 mm Petri dishes (AMES test)

All commercial brands are supported.

Controlled inlet flow

VITROCELL® exposure systems have been specifically designed and engineered to give researchers the possibility of directly exposing mammalian cells or tissue at the air/liquid interface. Thus, all cell types cultivated on microporous membranes can be used. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.


  • Suitable for COSTAR®, FALCON® and ThinCert® 6-well sized cell culture inserts
  • Adaptors for 12 and 24-well sized inserts
  • Individual media inlets and outlets for each cell culture insert compartment
  • Special inlet geometry of the aerosol exposure top for optimal particle deposition
  • Inlets made of stainless steel with a unique VITROGLIDE surface treatment
  • Base module made of electropolished stainless steel
  • Base module and aerosol exposure top with integrated water heating circuit
  • Control window for monitoring culture medium levels
  • Autoclavability of all components
  • Suitable for VITROCELL® Quartz Crystal Microbalance
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VITROCELL® 6/3, 6/4 and 6/6 CF

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