Home|Inhalation Toxicology|Exposure Systems|for 6-well inserts|6/3, 6/4 and 6/6 CF Stainless Steel

VITROCELL® 6/3, 6/4 and 6/6 CF Stainless Steel modules for 6-well sized inserts

The VITROCELL® 6 CF module system has been specifically designed and engineered to facilitate research of the direct exposure of human cell cultures to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of anatomical exposure.

Adaptors for 12 and 24-well sized, inserts make this exposure system an optimal, universal testing platform.

Base module

VITROCELL® 6/6 CF base module for 6 inserts

The base module is made of electropolished stainless steel for maximum durability and is fully autoclavable for 20 min. at 120° C and higher temperatures. A constant temperature within the unit (37° C / 99° F) is assured via water circuit heating. Therefore, an additional incubator is not required during exposure. The media are supplied individually to each well compartment. Optionally, media exchange can be carried out on a continuous basis using a precision media pump.

Cell culture insert for VITROCELL® 6/3, 6/4 and 6/6 CF Stainless Steel base module

The module has been designed for 3, 4 or 6-cell culture inserts (6-well size).

Universal module with optional adaptor sets for:

12-well sized inserts
Snapwell® inserts
24-well sized inserts
35 mm Petri dishes (AMES test)

Aerosol exposure top

Special sealing and connection mechanisms guarantee a hermetic connection of the base module with the aerosol exposure top.

The aerosol inlet-stream flows through specially shaped inlets. The stainless steel / VITROGLIDE inlets are specifically designed for aerosols containing nanoparticles. The aerosol exposure top features an in/outlet for heating the water circuit, ensuring corresponding temperatures with the base module. It is made of high-quality anodized aluminum.

option microbalance sensor for 6-well inserts

Microbalance Sensor – Additional option

A choice of modules equipped with 1 Quartz Crystal Microbalance for dose monitoring is also available.

Controlled inlet flow

Specifically designed inlets for optimal distribution and particle deposition.

More information about the VITROCELL inlet flow principle in our introduction

Features

Suitable for COSTAR®, FALCON® and ThinCert® 6-well sized cell culture inserts
Adaptors for 12 and 24-well sized inserts
Individual media inlets and outlets for each cell culture insert compartment
Special inlet geometry of the aerosol exposure top for optimal particle deposition
Inlets made of stainless steel with a unique VITROGLIDE surface treatment
Base module made of electropolished stainless steel
Base module and aerosol exposure top with integrated water heating circuit
Control window for monitoring culture medium levels
Autoclavability of all components
Suitable for VITROCELL® Quartz Crystal Microbalance