VITROCELL® 12/6 Stainless Steel

Stainless Steel modules for 12-well sized inserts


The VITROCELL® 12/6 module system has been specifically designed and engineered to facilitate the research of human cell cultures direct exposure to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of human physiological exposure.

Base module
(for higher throughput with 6 compartments / Static medium supply)

The VITROCELL® 12/6 modules are made of electropolished stainless steel. They are designed with six compartments for 12-well cell culture inserts and are fully autoclavable at 121° C (250° F) for 20 min. A transparent control window facilitates the external monitoring of media levels. Through the employment of a special adapter set, this module can also be flexibly combined for use with 24-well cell culture inserts. A constant unit temperature is guaranteed using a regulated flow of temperature-controlled water through the module.

The medium can be supplied gravimetrically using a bottle or syringe. This module is renowned in scientific circles for its reliability and durability.

More about 12/6 Stainless Steel

Aerosol exposure top

Special sealing and connection mechanisms guarantee a hermetic connection of the base module with the aerosol exposure top.

The aerosol inlet-stream flows through specially shaped inlets. The stainless steel / VITROGLIDE inlets are specifically designed for aerosols containing nanoparticles. The aerosol exposure top features an in/outlet for heating the water circuit, ensuring corresponding temperatures with the base module. It is made of high-quality anodized aluminum.

Controlled inlet flow

VITROCELL® exposure systems have been specifically designed and engineered to give researchers the possibility of directly exposing mammalian cells or tissue at the air/liquid interface. Thus, all cell types cultivated on microporous membranes can be used. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.

Option for microbalance sensor

The QCM sensor can be integrated in the exposure module. It is capable of measuring the deposited mass in nanogram/cm2 per second. Results are reported online by the VITROCELL® Monitor software. Data is presented in graphs and stored in MS Excel®.

Adaptor-Sets

Universal module with optional adaptor sets for:

  • 12-well sized inserts
  • 24-well sized inserts

All commercial brands are supported.

Features

  • Suitable for COSTAR®, FALCON® and ThinCert® 12-well sized cell culture inserts
  • For higher troughput
  • Autoclavability of all components
  • Base modules’ casing made of electropolished stainless steel for extreme durability
  • Base module with water heated base plate
  • Integration of the hyperboloid geometry of inlets into the aerosol exposure top
  • Dynamic dilution system part of delivery
  • Option: Control window for monitoring culture medium levels
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VITROCELL® 12/6 Stainless Steel

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