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VITROCELL® 12/6 Stainless Steel for 12-well sized inserts

The VITROCELL® 12/6 module system has been specifically designed and engineered to facilitate the research of human cell cultures direct exposure to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of human physiological exposure.

VITROCELL® 12/6 Stainless Steel for 12-well sized inserts base module

Base module (for higher throughput with 6 compartments / Static medium supply)

The VITROCELL® 12/6 modules are made of electropolished stainless steel. They are designed with six compartments for 12-well cell culture inserts and are fully autoclavable at 121° C (250° F) for 20 min. A transparent control window facilitates the external monitoring of media levels. Through the employment of a special adapter set, this module can also be flexibly combined for use with 24-well cell culture inserts. A constant unit temperature is guaranteed using a regulated flow of temperature-controlled water through the module.

The medium can be supplied gravimetrically using a bottle or syringe. This module is renowned in scientific circles for its reliability and durability.

Cell culture insert for VITROCELL® 12/6 Stainless Steel base module

The module has been designed for 6-cell culture inserts (12-well size).

Available adaptor set for 24-well sized inserts.

VITROCELL® 12/6 Stainless Steel for 12-well sized inserts aerosol exposure top

Aerosol exposure top with central aerosol supply

Special sealing and connection mechanisms guarantee a hermetic connection of the base module with the aerosol exposure top.

The aerosol inlet-stream flows through specifically shaped inlets. They are available in stainless steel or stainless steel with unique VITROGLIDE surface treatment for lowest adhesion results. The stainless steel / VITROGLIDE inlets are specifically designed for aerosols containing nanoparticles.

The aerosol inlets are connected to the distribution or dilution systems. Extraction from the module takes place via small holes using a controlled vacuum flow. VITROCELL® calibration valves, which are connected to a vacuum pump control flow rates effectively. The aerosol exposure top features an in/outlet for heating the water circuit, ensuring corresponding temperatures with the base module. It is made of high-quality anodized aluminum.

option microbalance sensor for 12-well inserts

Microbalance Sensor – Additional option

A choice of modules equipped with 1 Quartz Crystal Microbalance for dose monitoring is also available.

Controlled inlet flow

Specifically designed inlets for optimal distribution and particle deposition.

More information about the VITROCELL inlet flow principle in our introduction

Features

Suitable for COSTAR®, FALCON® and ThinCert® 12-well sized cell culture inserts
For higher troughput
Autoclavability of all components
Base modules’ casing made of electropolished stainless steel for extreme durability
Base module with water heated base plate
Integration of the hyperboloid geometry of inlets into the aerosol exposure top
Dynamic dilution system part of delivery
Option: Control window for monitoring culture medium levels