VITROCELL Systems

Exposure Principle 2 Single Droplet Sedimentation (Cloud Exposure) Single Droplet Sedimenation Systems are specifically designed for dose-controlled and spatially uniform deposition of liquid aerosols on cells. Test substances are chemicals or particles brought into suspension with e.g. PBS. The aerosol is applied for a short time of approx. 3–6 minutes. This method is well suited for scarce and expensive materials, such as new drug candidates or particle samples from the environment. Nebulization volumes range from 15 to 300 µl. Aerosolization is performed directy into the cell culture exposure chamber. Aerosolization can be repeated several times to obtain a doseresponse profile. VITROCELL® Cloud Alpha Years of experience and customer feedback led to the development of the new VITROCELL® Cloud Alpha. The design and enhanced functionalities offer an exceptional user experience. VITROCELL® Cloud Alpha MAX Is designed for lower nebulization volumes and very high depostion efficiency and combines high throughput testing with ease of use. VITROCELL® Cloud Alpha MOVE For automated and repeated row-by-row exposure of 12-, 24- and 96-well sized cell culture inserts. The ideal device to obtain a dose-response relationship in one experiment . Cloud Exposure Systems 12x ! Phase 1 Emission of Cloud Phase 3 Gravitational Settling 12x ! Phase 2 Homogeneous Mixing 12x ! Continuous Flow Dry Powder Single Droplet Exposure Systems Continuous Flow Dry Powder Single Droplet Exposure Systems Dry Powder Continuous Flow Single Droplet Exposure Systems 8

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