VITROCELL Systems

The VITROCELL® sQCM 12 is the next step in the evolution of dosimetry methods in cell culture exposure systems. It simplifies the usage of conventional Quar tz Crystal Microbalances suitable for VITROCELL® 12 modules while maintaining the working principle, precision and accuracy of the balances you’re used to. We have redesigned the entire sensor from scratch, enabling not only extremely high stability and exact measurements, but also eliminating the need for tools during service and cleaning for maximum user-friendliness. Easy crystalreplacement without tools through bayonet connection of the sensor par ts. Thanks to the wide compatibility of the sQCM 12 sensor, it is ideal for the validation of the mass deposition of exposure substances, either during or after an experiment . Its broad measuring range and shape reminiscent of a cell-culture insert make it a convenient aid in acquiring single exposure doses or complete dose-response curves. Use case This novel solution minimizes the time you have to spend to perform cleaning and crystal exchange: it now only takes a mere minute. Eliminating the need for screwdrivers, our new design uses a bayonet catch to connect the individual sensor parts. In Continuos Flow Systems, results are seen online, enabling you to measure cumulated depositions star ting from 170 ng/cm2 reliably. In Cloud systems, the sQCM 12 provides the additional benefit of real-time control over the process and exact readings af ter removal of humidity (dotted line on the right). The innovative sensor design is fully compatible with any VITROCELL® module for 12-well sized inser ts, be it Cloud, Cloud Alpha, Continuous Flow or any other VITROCELL® exposure system for this inser t size. Simplified use and wide compatibility VITROCELL® sQCM 12 High precision r al-time dose monitoring PRODUCT NEWS Platzhalter für Foto #1 Platzhalter für Foto #2 The VITROCELL® sQCM 12 is the next step in the evolution of dosimetry methods in cell-culture exposure systems. It simplifies the usage of conventional quartz crystal microbalances suitable for VITROCELL® 12 modules while maintaining the working principle, precision and accuracy of balances you’re used to work with. To pair this with extremely high stability, as well as exactitude of your measurements, we have reworked the sensor from scratch, making its service and cleaning completely tool-free. Wide Compatibilty Even though the sensor is a complete redesign, it is fully compatible to any VITROCELL® module for 12-well inserts, be it Cloud, Cloud α, Continuos Flow or any other type of exposure system in this format. Use Case With the sQCM 12 sensor being able to be placed in all medium compartments of the devices stated above, it is an optimal tool to validate mass deposition of exposure substances either during or after an experiment. Its broad measuring range and cell-culture insert like shape render it a convenient aid in acquiring single exposure doses or complete dose-response curves. 0 4.000 8.000 12.000 16.000 20.000 0 120 240 360 480 600 Deposition / (ng/cm²) t / (s) Performance simplified This novel creation shrinks the time you have to spend to perform cleaning or servicing tasks down as far as possible. The necessary crystal change now only takes a mere minute. Having to think about screwdrivers is now a thing of the past. While in Continuos Flow systems, results are seen immediately, enabling you to measure mass depositions of only 170 ng/cm; reliably. In Cloud systems, the sQCM 12 rewards you with a real-time process control and exact readings after removal of humidity (dotted line on the right). VITROCELL Cloud α 12 – Exposure of 0.2 mL 0.015 mg/mL Fluorescein and 9.54 mg/mL KCl VITROCELL® Cloud Alpha 12 – Exp sure of 0.2 mL 0.015 mg/mL Fluorescein and 9.54 mg/mL KCl Designed for maximum user-friendlyness. VITROCELL® S CM 12 Microbalance Sensor For Real-Time Dose Monitoring 162

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