Advanced in vitro exposure systems.

The QCM - Online Dose Measurement with high relative Humidity

11. Sep. 2009

European Aerosol Conference. Karlsruhe, Germany.

September 06-11, 2009

Authors
S. Mülhopt, A. Comouth, A. Grotz, T. Krebs, H.-R. Paur

Institute for Technical Chemistry, Thermal Waste Treatment Division, Forschungszentrum Karlsruhe GmbH, Karlsruhe, Germany
Institute for Meteorology and Climate Research, Atmospheric Aerosol Research Department, Forschungszentrum Karlsruhe GmbH, Karlsruhe, Germany
VITROCELL Systems GmbH, Waldkirch, Germany

 

The shown method first time provides an online dose measurement for in vitro exposure experiments at the air-liquid interface also under high humidity conditions.  Human lung cell cultures were tested for different biological responses like the viability (LDH, AlamarBlue) as well as the release of IL-8.

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