Advanced in vitro exposure systems.

Exposure of a multi-cellular in vitro model of human airway tissue to the whole cigarette smoke

10. Mar. 2008

Respiratory and Critical Care Medicine

Vol 177 (Abstracts Issue): pA728 (2008)

Authors
Walsh, P.T., Chalupowicz, D.G., Frankowski, R., Barnette, M.

Discovery Biology, Respiratory CEDD, GlaxoSmithKline, Upper Merion, PA19406, USA

 

HBE cells were exposed in a single and repeated whole smoke situation. The cells were analysed for changes in gene expression (RT-PCR) and cell viability was confirmed using the MTT assay and release of IL-1, IL-6 and IL-8.

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