Biological effects in human lung cells exposed to platinum nanoparticle aerosol

September 11, 2009

September 06-11, 2009

Authors
S. Diabaté, C. Weiss, S. Mülhopt, H.-R. Paur, V. Niedetzky, M. Seipenbusch

Institute for Toxicology and Genetics, Forschungszentrum Karlsruhe, 76021, Karlsruhe, Germany

Institute for Technical Chemistry
, Forschungszentrum Karlsruhe, 76021, Karlsruhe, Germany

Institute for Mechanical Process Engineering and Mechanics
, University Karlsruhe, 76131, Karlsruhe, Germany

 

For the bioassay they exposed platinum nanoparticles to BEAS-2B and A549 cells, both co-cultured with differentiated THP-1 macrophages, growing on Transwell inserts. The responses of the cells were analyzed by measuring the viability, LDH and IL-8. 

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